When a stem cell divides, it has the potential to either remain as a stem cell (process known as «self - renewal») or to
become a different type of cell with a more specialized function («differentiation»).
Not exact matches
These
cells, which can
become several
different types of blood
cells, are similar to the specialized stem
cells found in bone marrow that can churn out new blood
cells.
«Growing stem
cells on synthetic surfaces with
different levels
of compliance showed that stem
cells would
become a
different cell type depending solely on the mechanical environment they perceive.
Stem
cells are capable
of becoming many
different tissue
types, including neurons.
Adult stem
cells: They have less flexibility and «stemness» to change into
different cell types, but they can still produce new
cells, specialized to
become part
of a particular organ or tissue, such as muscle
cells or neural
cells.
To create
different cell types in the lab, stem
cells must be coaxed down the road
of determination — the branching paths that fetal
cells normally travel to
become neurons, skin
cells, muscle
cells, or any number
of other
cell types.
«The organization
of cell colonies and phenotypic switching between
different types of colonies
becomes a lot more flexible and rapid with reversible aneuploidy than if it depended on random mutations in the genes,» Skupin says.
These findings will open up new ways to improve the efficiency
of cell reprogramming and to drive stem
cells to
become different types of specialised
cell.
For instance, the trials underway in China and Australia use neural progenitor
cells that can grow to
become a variety
of different cell types.
«These are interesting results proving it is theoretically possible to «regress»
cells back to an earlier stage in development when they are self - perpetuating and still have the potential to be directed to
become a whole range
of different cell types, whether nerve
cells, heart muscle or bone.
(Adult stem
cells, on the other hand, are much more limited in their potential; they can usually only
become a few
different cell types, and consequently are not applicable for treating as wide a variety
of diseases as hESCs are.)
The researchers were able to «reprogram» adult skin
cells to
become cells of a
different tissue
type.
MSCs hold great potential for the field
of regenerative medicine, as they can
become many
different types of cells (they're «multipotent»), most typically bone, cartilage, and fat
cells.
Although cancer stem
cells have been identified in many
different types of cancer, it is
becoming increasingly clear that the properties
of these
cells may vary greatly among the
different tumor
types.
There are over 200
different types of cells in the human body, many
of which can
become neoplastic.
As time passes and the
cells start dividing further and further, they start specializing into
becoming a specific
type of tissue which has a specific function, thus forming all the
different parts that comprise a human.
Any
cell can
become this way — that is why we have so many
different types of cancer.