In those studies, sorted progenitor cells, some of which could
become endothelial cells, were introduced into the heart.
Not exact matches
The onset of tube structure formation could be visualized as early as 4 h after plating for most
endothelial cell lines, with extensive networks
becoming visible within 12 h after plating.
Such a depot or niche of
endothelial stem - like
cells would be analogous to the epithelial stem
cells located in the anterior limbus that supply
cells to the basal epithelium as transient amplifying
cells, the
cells that
become committed to the state of terminal differentiation [11,15].
Additionally, ERCs were reported to be able to differentiate into, or
become,
cells from the three different germ layers (see the previous post on MSCs for more details): mesoderm (muscle, bone, fat, cartilage, and
endothelial cells), ectoderm (neurons), and endoderm (liver, pancreas, and lung
cells)(Meng et al., 2007; Patel et al., 2008).
The
endothelial cells became vessels, recruited fibroblasts and caused them to differentiate into smooth muscle
cells.
At the same time, the protein Vascular
Endothelial Growth Factor (VEGF) stimulates blood supply for the damaged tissue, Fibroblast Growth Factor - 2 (FGF - 2) stimulates the damaged
cells to grow and reproduce themselves, Transforming Growth Factor - beta (TGF - beta) stimulates cartilage to grow, and Stem
Cell Factor (SCF) stimulates your native inactive stem
cells to
become activated and assist in the repair of the damaged tissue.
Bodybuilding.com says that «When a man
becomes sexually stimulated either through physical contact or other sensory stimuli, a signal is sent from the brain to
endothelial cells in the penis to release nitric oxide (NO).»