Rather than being a secondary effect of these protein pathologies, as experts had previously thought, this process may begin well
before plaques form.
«If you wanted to target APOE to affect the amyloid process, the best thing would be to start
before the plaques form,» Holtzman said.
Not exact matches
To better explain this finding, the team turned to yet another protein, amyloid beta — which in its soluble
form,
before building up and hardening into
plaques, has already been found to be toxic to the synapses.
Among other results, he has found that the
plaque -
forming a-beta protein disrupts neuronal function and connectivity even
before amyloid
plaques accumulate, a finding with important implications for understanding AD pathogenesis.
Home Care Removing
plaque before it
forms tarter is the most important step in preventing periodontal disease.