Sentences with phrase «behavioral abnormalities in»

Heston also found behavioral abnormalities in many of the other children (Eysenk, 1982).
Harry Han, Carolyn A. Allen, Christie M. Buchovecky, Michael J. Yetman, Heather A. Born, Miguel A. Marin, Shaefali P. Rodgers, Bryan Song, Hui - Chen Lu, Monica Justice, Frank J. Probst, and Joanna L. Jankowsky (2012) «Strain background influences neurotoxicity and behavioral abnormalities in mice expressing the tetracycline transactivator», Journal of Neuroscience 32:10574 - 10586.
Dr. Mucke has spent most of his career uncovering the molecular and cellular mechanisms that cause memory loss and behavioral abnormalities in Alzheimer's disease and related conditions.
Interestingly, Nav1.1 - deficient interneuron transplants were sufficient to cause behavioral abnormalities in wild - type mice, indicating the key functional role of interneurons and Nav1.1 for cognitive functions.
Remarkably, giving animals injections of lithium salts — which mimics WNT signaling by inhibiting the molecule GSK3 — or giving animals a more specific GSK inhibitor, the researchers were able to restore normal synapse and spine numbers and also improve some of the most significant psychiatric - like behavioral abnormalities in these mice.
VPA has a known link to autism in humans and also induces autism - like cognitive and behavioral abnormalities in mice.

Not exact matches

As for the viral theory, prenatal infection has begun to be indicated in the development of behavioral abnormalities and structural differences in the prefrontal cortex.
I only read the abstract so far, but it seems to be talking about, as you pointed out, «behavioral abnormalities and structural differences in the prefrontal cortex.»
Inherited or acquired abnormalities in brain chemistry create an altered response to alcohol which in turn causes a wide array of physical, psychological, and behavioral problems.
Waber and her colleagues at hospitals in five other cities screened thousands of children in order to get a sample that was representative of the diverse demographics of the U.S. Study participants could not have behavioral or cognitive abnormalities or any risk of developing a mental or neurological disorder.
Abnormalities in brain structure during critical periods in development have often been associated with negative outcomes, such as learning disabilities and behavioral disorders.
«I am especially excited about the improvements we observed in cognitive and behavioral dysfunctions because these abnormalities are particularly hard on the kids — and their parents,» said first author Ania Gheyara, MD, PhD, a staff scientist at Gladstone who is also affiliated with the UCSF Department of Pathology.
«We hope to advance our research in order to elucidate genetic defects that result in behavioral abnormalities,» Yamamoto said.
When the researchers silenced the genes in the peripheral nerves of adult animals, they were still hypersensitive to light touch, but they didn't display the behavioral abnormalities seen in the animals that had the gene silenced from birth.
«We wanted to find the link between the abnormal structure of synapses in the FXS mouse, and the behavioral abnormalities at the level of brain circuits; that had not been previously established,» said senior author Dr. Carlos Portera - Cailliau, an associate professor in the departments of neurology and neurobiology.
«Studies of fetuses and babies with the telltale small brains and heads of microcephaly in Zika - affected areas have found abnormalities in the cortex, and Zika virus has been found in the fetal tissue,» says Guo - li Ming, M.D., Ph.D., a professor of neurology, neuroscience, and psychiatry and behavioral science at Johns Hopkins» Institute for Cell Engineering.
FTD is known as young - onset dementia and is characterized by behavioral abnormalities including a decline in cognitive, motor, and language function.
This suggests that NF - kB may be at the center of the behavioral abnormalities observed in FTD.
Mice that are homozygous for the R26 - stop - EYFP mutant allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities.
Francesco Longo is interested in understanding the synaptic and behavioral abnormalities associated with autism spectrum disorder, with particular attention to striatal dysfunction in fragile X syndrome model mice.
In the most common FTD subtype, behavioral variant FTD, patients present with social dysfunction, apathy, disinhibition, repetitive behavior, and other behavioral abnormalities (Rascovsky et al., 2011; Karageorgiou and Miller, 2014).
Howard Hughes Medical Institute researchers have produced a genetically altered mouse that exhibits behavioral abnormalities that are strikingly similar to those observed in humans with schizophrenia...
We need to understand how billions of neurons in different parts of the brain talk to each other, and how malfunctions in neural connections get expressed as behavioral abnormalities
Pilot randomized trial demonstrating reversal of obesity - related abnormalities in reward system responsivity to food cues with a behavioral intervention.
It is known that motor abnormalities in CAG 94 KI and CAG 140 KI mouse models are present from an early age, with a delayed onset observed in the CAG 94 KI model as compared to CAG 140 KI; in addition, overt behavioral deficits were observed after 2 years of age in the CAG 140 KI mouse model (Menalled et al., 2003, Hickey et al., 2008).
Reversal of behavioral and metabolic abnormalities, and insulin resistance syndrome, by dietary restriction in mice deficient in brain - derived neurotrophic factor
There is no scientific evidence that de-clawing leads to behavioral abnormalities when the behavior of de-clawed cats is compared with that of cats in control groups.
The behavioral abnormalities seen in the hyperthyroid cat have been well described in the literature, and mimic closely the restlessness, insomnia and irritability or aggression described in humans with thyrotoxicosis.
A Yorkie with this condition might exhibit some or all of the following symptoms: small stature, poor muscle development, behavioral abnormalities, unresponsiveness, seizures, and so on; however, if treated by a veterinarian, the condition is most often reversible in time.
In general, the Golden Retriever is very calm, with any behavioral abnormalities (aggression, hostility, depression) being viewed as a serious fault in the breeIn general, the Golden Retriever is very calm, with any behavioral abnormalities (aggression, hostility, depression) being viewed as a serious fault in the breein the breed.
The two most common causes are FIC (feline idiopathic cystitis) and urolithiasis (stones in the urinary tract); bacterial infections, cancer, behavioral issues, neurologic deficits, and conformation abnormalities can all play a role in FLUTD.
Instead, you will have to determine if there have been any behavioral changes or abnormalities in your elderly loved one.
So, behavior analysts work mainly in research institutes and public offices where their main duty is to proffer solutions to behavioral abnormalities.
The unique structural brain abnormalities that may be related to behavioral problems and sustained selective attention difficulties, and that have also been found in moderately preterm children, are also important (Kinney 2006).
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