Sentences with phrase «benefit over the risks»

Society's focus on benefits over risk gave tech companies free rein — until the resulting abuses couldn't be overlooked.

Not exact matches

Even investors with generous benefits and pension plans must take on some risk to build a decent nest egg, «so do you really care if markets go up or down 15 % over a six - month period?»

Given the potential opportunity cost associated with avoiding the stock market — which could be as much as $ 3.3 million over 40 years, according to NerdWallet — as well as the benefits of compound interest over four decades, the bigger risk may be not investing at all.

Costs were brought down by filming in North Carolina for tax benefits, and risk was reduced by selling off foreign rights for over $ 50 million.

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

You get extra risk with no extra benefit over, as Allan Roth put it, owning the world.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Such risks and uncertainties include, but are not limited to: our ability to achieve our financial, strategic and operational plans or initiatives; our ability to predict and manage medical costs and price effectively and develop and maintain good relationships with physicians, hospitals and other health care providers; the impact of modifications to our operations and processes; our ability to identify potential strategic acquisitions or transactions and realize the expected benefits of such transactions, including with respect to the Merger; the substantial level of government regulation over our business and the potential effects of new laws or regulations or changes in existing laws or regulations; the outcome of litigation, regulatory audits, investigations, actions and / or guaranty fund assessments; uncertainties surrounding participation in government - sponsored programs such as Medicare; the effectiveness and security of our information technology and other business systems; unfavorable industry, economic or political conditions, including foreign currency movements; acts of war, terrorism, natural disasters or pandemics; our ability to obtain shareholder or regulatory approvals required for the Merger or the requirement to accept conditions that could reduce the anticipated benefits of the Merger as a condition to obtaining regulatory approvals; a longer time than anticipated to consummate the proposed Merger; problems regarding the successful integration of the businesses of Express Scripts and Cigna; unexpected costs regarding the proposed Merger; diversion of management's attention from ongoing business operations and opportunities during the pendency of the Merger; potential litigation associated with the proposed Merger; the ability to retain key personnel; the availability of financing, including relating to the proposed Merger; effects on the businesses as a result of uncertainty surrounding the proposed Merger; as well as more specific risks and uncertainties discussed in our most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.cigna.com as well as on Express Scripts» most recent report on Form 10 - K and subsequent reports on Forms 10 - Q and 8 - K available on the Investor Relations section of www.express-scripts.com.

Saunders, the president of the Vancouver and District Labour Council, says that Canadian workers and their pensions are more exposed to risk during market trouble because of the successful campaign over the past decades to move from defined benefit pensions, which guarantee a certain monthly amount when you retire, to defined contribution plans, promoted by market enthusiasts.

We have benefited from this year's rally in stocks and bonds (our Multi Asset Risk Strategy ETF Model Portfolio has a Sharpe ratio of over 3 this year — and that's with no leverage), but we are managing our risk by incorporating asset classes such as gold through the iShares Gold Trust (IAU); liquid alternatives through the IQ Hedge Multi-Strategy Tracker ETF (QAI), long - dated Treasuries through the iShares 20 + Year Treasury Bond ETF (TLT)-- each of which diversify our portfolio risk and carry well within an ETF portfolio constrRisk Strategy ETF Model Portfolio has a Sharpe ratio of over 3 this year — and that's with no leverage), but we are managing our risk by incorporating asset classes such as gold through the iShares Gold Trust (IAU); liquid alternatives through the IQ Hedge Multi-Strategy Tracker ETF (QAI), long - dated Treasuries through the iShares 20 + Year Treasury Bond ETF (TLT)-- each of which diversify our portfolio risk and carry well within an ETF portfolio constrrisk by incorporating asset classes such as gold through the iShares Gold Trust (IAU); liquid alternatives through the IQ Hedge Multi-Strategy Tracker ETF (QAI), long - dated Treasuries through the iShares 20 + Year Treasury Bond ETF (TLT)-- each of which diversify our portfolio risk and carry well within an ETF portfolio constrrisk and carry well within an ETF portfolio construct.

High profits may be justified if novel products offer significant benefits to patients (thus producing indirect economic value through the patients» restored health) or if they represent significant pharmacologic advances over their predecessors — offering new mechanisms of actions and emblematic of high - risk research.

At present, investors have no reasonable incentive at all to «lock in» the prospective returns implied by current prices of stocks or long - term bonds (though we suspect that 10 - year Treasuries may benefit over a short horizon due to continued economic risks and still - unresolved debt concerns in Europe, which has already entered an economic downturn).

Hypothetically, a venture capital fund holder of Series A might not want a company to argue hard over merger valuation with an acquiror if there is no marginal benefit to the fund and there is a risk that the deal may fall apart.

Furthermore, the report by Aidenvironment, which analyzed 40 previous independent research studies, surveying over a hundred business leaders across four sectors, found a range of business benefits from certification — from improved market access, profitability and production to enhanced reputation and reduced risk for certified businesses.

Longer duration of breastfeeding may or may not affect the appearance of your breasts, but it will reduce the risk for breast cancer over your lifetime, in addition to the many other health benefits to you and to your breastfed baby.

An unvaccinated child is a health risk to babies too young to vaccinate and to children who are in the process of receiving a series of vaccinations over a period of time until the full benefit / immunity is attained.

It is up to parents to make sure that the helmet their child wears fits properly, maintains that fit over the course of a season, and has been properly reconditioned, and, if the football program does not buy impact sensors for the whole team, to consider buying one on their own, weighing the benefits of knowing the magnitude and frequency of the hits that their child is taking to the head against the risk that adding a two - ounce piece of plastic to the inside or outside of their helmet may void the manufacturer's warranty and NOCSAE certification or increase the risk that the protection the helmet's polycarbonate shell provides against skull fractures will be compromised;

Then, we transitioned him to only watching videos during poop changes (when the benefit of avoiding getting poop all over the floor outweighed the risk of him dialing Grandpa for the 78th time).»

I don't drive personally, because over the course of my lifetime, I don't like the risk level relative to the benefit.

As important as it is, however, to promptly treat depression, some are voicing concern over whether the risks of antidepressant medications outweigh the benefits.

As a result, prevention and treatment approaches that decrease relapse risk and / or increase the intervals between major depressive episodes over the long term hold the greatest promise to benefit mothers and children.

Studies are showing that, not only do antibacterial soaps lack any benefits over using regular old soap and water, but that they could be harmful in that they potentially increase the risk of drug - resistance.

Starting from today lone parents whose children are aged 12 or over will be forced to actively seek work for a minimum of 16 hours per week or risk losing 40 per cent of their benefit.

If Marcie's # 225 earnings are derived from being on or near the minimum wage, then there is a double hit for her because she also can not salary sacrifice to save 12 per cent National Insurance, if such an arrangement would take her pay below the level of the applicable minimum wage rate (# 7.83 per hour in 2018/19 for those aged 25 and over).3 Anne Fairpo said: «One of the concerns about allowing the lowest earners to sacrifice salary has been the risk of their pay dropping below the point at which entitlement to contributory benefits is triggered (the Lower Earnings Limit - # 116 per week in 2018/19).

MTD is capable of delivering benefits over the years to come, but there is a risk that many disabled people in business will suffer a real burden if they find they are mandated not only to transact with HMRC digitally, but also to keep records in a prescribed digital format.

«When we're talking about cuts of this scale, over this short a timescale, we're inevitably going to be talking about job losses, which will mean rising unemployment, increased benefit payments, reduced tax revenue and a real risk of a double - dip recession,» she said The government expects to save up to # 120m this year by freezing recruitment across the board in government departments, agencies, and quangos.

In 2009, based on evidence that the benefit - risk ratio for mammography screening is higher among women over 50 and with less frequent screening, the U.S. Preventive Services Task Force (USPSTF) reversed its previous recommendation of mammography every one to two years beginning at age 40, and recommended routine screening every two years starting at age 50, the researchers noted.

«Other studies have suggested some benefit of neuraxial over general anesthesia, but they looked at very limited outcomes, primarily at risk of bleeding and blood transfusions.

These events — even more than the use of nuclear weapons at the end of World War II — launched an ongoing public debate over whether the risks of radiation exposure outweigh the benefits of nuclear technology.

Hormone replacement therapy has been controversial over the past few decades as studies have associated it with both health benefits — lowering the risk of osteoporosis and improving some measures of heart health, for example — and risks, including links to cancer and stroke.

Although a meta - analysis of statins suggests that healthy people over 50 take cholesterol - lowering drugs as a preventative measure, some researchers argue the benefits may not outweigh the risks

The surprising conclusion sparked a debate over the risks and benefits of screening for the disorder.

Debates are now erupting over the benefits and ecological risks of releasing such insects into the wild — and whether gene drives could also thwart invasive species such as Asian carp and cane toads, or combat other animal - borne pathogens such as the one causing Lyme disease.

The study focuses on how these approaches help coastal communities reduce their risk of flooding and erosion, as well as additional benefits, and the tradeoffs when decision makers choose one type over another.

«The absence of a significant survival benefit associated with one prosthesis type over another focuses decision making on lifestyle considerations, including the burden of anticoagulation medication and monitoring, and the relative risks of major morbidity — primarily stroke, reoperation, and major bleeding events,» the authors write.

And, Shah says, a comprehensive package of interventions that coupled targeted screening of high - risk groups, improved linkage to care, and enhanced retention and re-engagement in care was projected to have the greatest benefit, averting a projected 752,000 new HIV infections and 276,000 AIDS deaths at a cost of $ 96 billion over 20 years, or $ 45,300 per QALY gained.

The Johns Hopkins team analyzed the data to identify how many minimally invasive surgery procedures hospitals could be performing based on standard qualifications for four different operations: appendectomy, colectomy and hysterectomy, all procedures for which minimally invasive surgery has shown significant advantages over open procedures, and lung lobectomy, an operation for which the jury is still out on the risks versus benefits.

It has been previously rejected by the FDA, once in 2010 over concerns of its efficacy and once again in 2013, when the FDA questioned whether the side effect risks outweighed the benefits.

The study offers new data in an ongoing debate over the risks and benefits of using epinephrine to treat cardiac arrest, an often - fatal condition in which the heart stops beating.

The original issues concerned complex risk - benefit calculations over whether a particular formulation of MMR's attenuated live - virus mumps component was associated with a too - high incidence of transient meningitis.

Researchers hypothesize that crossover rates have evolved to balance the benefits of crossing over with the risks of selfish DNA.

Certainly if you continue, as I would recommend to use the single vaccine, you do not incur a greater risk of those diseases in the children, so that you do not lose the benefits of vaccination if you space them over time.

The trial was stopped early based on health risks that exceeded health benefits over an average follow - up of 5.2 years.

The results of this study suggest that if consumed over time, hibiscus tea can reduce the risk of stroke and heart attack, which is another huge benefit of hibiscus tea.

But in a recent 4.3 - year analysis of 18,991 men and women over 35, it was found that while a Mediterranean diet could lower cardiovascular disease risk, only wealthier, more educated folks got those benefits.

Men under age 50 do have a * slightly * increased risk of heart disease with levels over 300, but levels just under 300 removed this risk and maintaining levels at 200 or lower did not offer any more statistical benefit.

CT screenings are now recommended for lung cancer screenings in people who are at high risk (long - term smokers over 55, in addition to other risk factors), but for other people, the risks of screening generally outweigh the benefits.

Cost and risk / benefit ratio over time must be taken into consideration.

A recent review of pooled research demonstrates that higher levels of aerobic exercise can significantly lower the risk of over a dozen different forms of cancer — with as little as 20 minutes a day providing cancer - fighting benefits.

In fact, we're so confident that you'll LOVE our bone broth (over 1500 five - star reviews), that we'd like to offer you a way to enjoy the benefits of bone broth at no risk to you.