«Tau aggregates to form the hall - mark tangles of Alzheimer's disease and serves as
the best marker of disease progression.
Not exact matches
Think
of people declining to get tested for the genetic
markers of a hereditary
disease, or a smoker whose cigarette packs might as
well have that warning from the Surgeon General printed in invisible ink.
As
well, many other gene
markers for grain - mediated injury have been described, thus placing many into the category
of gluten intolerant, but not truly having celiac
disease.
FACT: Diagnosis
of coeliac
disease starts with blood testing, in which doctors study the series
of antibodies that provide a
good marker of tendency to have the illness.
Household income has been shown to interact with child growth in Brazil.21 A US study
of diarrhoeal
disease found no interaction between breast feeding and household income.8 Household income, like social class, may not be a
good marker of transmission risk.
Now with an extensive and diverse collection
of representative apple genomes, thorough and careful analyses have allowed Fei's group to distinguish important genetic
markers that will greatly aid breeders in their quest for
better apples — be it for
disease resistance, shelf - life, taste, or even size.
«It's
good to see this type
of study advance, as we desperately need noninvasive and low - cost
markers for Alzheimer's
disease,» Hendrix says.
Indeed, low birth weight, a
marker of impaired fetal development, is associated with increased everyday levels
of inflammatory
markers as
well as greater risks
of heart
disease, diabetes, depression and schizophrenia in adults.
In future studies, the team plans to use the model to
better understand how microbes, host factors and inflammatory
markers interact to produce the hallmarks
of inflammatory
disease in the intestine.
Two proteins, which have not previously been linked to pre-eclampsia risk, were shown to be at least as
good a predictor
of disease risk as the current
best marker, placental growth factor,.
«Our ability to pinpoint CRP levels as being significantly elevated before and after postoperative delirium onset establishes CRP as a risk
marker, as
well as a
disease marker, for delirium,» said Sarinnapha Vasunilashorn, co-first author
of the study, along with Simon Dillon, also
of BIDMC.
«The distinct neural
markers associated with cognitive performance and GWI revealed in our study can be useful for future research to objectively measure the efficacy
of treatments for GWI as
well as other brain disorders related to the same neurotransmitter system, like Alzheimer's
disease.»
People have realized that in order to
better diagnose
diseases like cancer, he says, you need information from a variety
of sources, whether it's fluorescence imaging, optical imaging or biochemical
markers.
Replicating Venter's $ 70 million technological feat is too costly for most
of us, and it's not clear what
good it would serve to know that, like Venter, one has a genetic
marker for wet earwax — or Alzheimer's
disease, which can't be prevented or cured.
Our diets can also change our metabolism as
well as the levels
of circulating factors (hormones, lipids, etc.) which may be
markers for
disease risk.
SRM - MS analysis will permit us to directly use small - sized samples, such as the individual CSF samples, enable verification
of marker candidates that currently do not have available antibodies (hence not amenable to conventional analyses such as ELISA or Western blots), and provide robust statistical analyses on individual candidate
markers or combinations
of them to determine which would make the
best biomarker (s) for a particular
disease condition.
«There are few
good biological
markers for this
disease and miRNA could help unravel many
of its complexities.»
Even further, studies on high - fat diets show that increased consumption
of saturated fat has beneficial impacts on cardiovascular
disease risk
markers, including decreasing the level
of triglycerides, fasting glucose, blood pressure, as
well as increasing HDL cholesterol blood levels.
«Finding this association with a strong
marker of Alzheimer's
disease risk reinforces the idea that being underweight as you get older may not be a
good thing when it comes to your brain health,» he added.
Excess testosterone also tends to negate the benefits
of testosterone supplementation, which include
better mood, increased energy, clearer thinking, increased muscle mass and improved heart
disease and diabetes
markers.
It has been seen to improve diabetes and high cholesterol in a number
of clinical studies, as
well as improve risk
markers of cardiovascular
disease and even constipation.
The claim: That eating for your blood type makes it easy to lose weight, have more energy and avoid chronic
diseases from autoimmune
disease to heart
disease to cancer, because the ABO
markers are a sign
of your ancestral lineage and what you might be
best adapted to eat.
Telomere length is arguably the
best marker of biological age, and shorter mean telomere length, usually measured in your white blood cells, is associated with increased risk
of heart
disease, obesity, cancer, stroke, dementia, and premature death (2).
«Given the high content
of certain specific polyphenols in the juice blend, the increased antioxidant protection [in the body] after consumption
of the juice blend, and the anti-inflammatory capacity in vitro, further research is warranted to evaluate whether juice blend consumption may provide reversal
of risk
markers in subjects with conditions such as arthritis, obesity, chronic viral
diseases, cardiovascular
disease and compromised cognitive function, as
well as other conditions associated with chronic inflammation,» wrote lead author Gitte Jensen from Holger NIS Inc., a contract research laboratory.
Before attempting to treat any intestinal, immune, or other
disease through a restrictive dietary change, a stool test may be the
best way to begin, to look at
markers that indicate how
well the gut is actually functioning, and to assess the diversity
of the gut microbiota.
An elevation
of lysozyme or calprotectin (biomarkers
of inflammation, some labs may use one or the other
marker) is an indication
of intestinal inflammation, and it may be an indication
of inflammatory bowel
disease (ulcerative colitis or Crohn's
disease), but may be found in celiac patients as
well.
But, given «the capacity
of [methionine restriction] to decrease the rate
of [free radical] generation in internal organs, to lower
markers of chronic
disease, and to increase maximum longevity, ironically converts such «disadvantage» into a strong advantage and [it] fits
well with the important role
of [beans] in healthy diets like the [traditional] Mediterranean diet.
Hopefully, as breeders take advantage
of the MRI procedure for their breeding stock, we may be able to have a
better grasp
of the
disease; however, in talking with respected breeders the world over, we have found that most believe that we will not eradicate the
disease until we find a gene
marker.
These abnormalities tend to cluster in the same individuals.18, 19 Evidence shows that the clustering
of metabolic risk
markers in adulthood is associated with elevated risk
of developing cardiovascular
disease, diabetes, and dementia in later life.18, 20 Importantly, depression, inflammation, and the clustering
of metabolic risk
markers frequently co-occur in the same individuals, and their co-occurrence is associated with the greatest
disease risk.20, 21 To improve life quality in aging populations, it is critical to gain a
better understanding
of the origins
of these 3 age - related -
disease risks.