GAD, myelin basic protein, asialoganglioside, alpha and
beta tubulin, cerebellar, synapsin: Neurological autoimmunity
Tubulin itself is a globular protein which consists of two polypeptides (alpha and
beta tubulin).
Immunohistochemistry of paraffin - embedded human brain tissue slide using 66240 -1-Ig (
beta Tubulin antibody at dilution of 1:400 (under 10x lens)
Immunohistochemistry of paraffin - embedded human breast cancer tissue slide using 66240 -1-Ig (
beta Tubulin antibody at dilution of 1:400 (under 10x lens)
An alpha and
beta tubulin heterodimer is the basic structural unit of microtubules.
ICC / IF image of
beta Tubulin staining in HeLa cells.
Microtubule strands assemble from subunits of alpha and
beta tubulin proteins that form dimers.
Assembling alpha -
beta tubulin dimers involves six known genes, Al - Bassam said.
Building from two subunits, alpha and
beta tubulin, this protein assembles into microtubules that play a vital role inside cells — giving structure, pushing or pulling other things around, or providing a track on which other molecules can pull themselves along.
The energy maybe required to build stable alpha and
beta tubulin assembly.
Beta tubulins can selectively (and reversibly) allow GTP to hydrolyze; they take on water to become guanosine diphosphate (GDP).
The alpha and
beta tubulins, which are each about 55 kDa MW, are homologous but not identical.
Not exact matches
Microtubules are hollow cylinders with walls made up of
tubulin proteins — alpha (green) and
beta (blue)-- plus EB proteins (orange) that can either stabilize or destabilize the structure of the
tubulin proteins.
Most importantly, they found that the active site of TTLL7 is ideally positioned to contact the negatively charged «
beta - tail» of
beta -
tubulin, one of the two protein building blocks of the microtubule polymer (alpha - and
beta -
tubulin).
We observed a modest decrease in cell cycling and some induction of the neuronal marker
beta - III
tubulin, as quantified here.
There are five
tubulins in human cells: alpha,
beta, gamma, delta, and epsilon.