Sentences with phrase «beta adrenergic»

Cholesterol, HDL, LDL, LDL / HDL Ratio, Cholesterol / HDL Ratio, Triglycerides, Diuretic in urine, and Beta Adrenergic Blockers

I now have increased beta adrenergic sensitivity and idiopathic postprandial syndrome as a direct result.

«Diazepam Increases Intracellular Calcium and Contraction Following Beta Adrenergic Stimulation In Myocytes»; Anesthesia & Analgesia 90: S56, 2000.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

Not exact matches

The alpha 2 and beta 2 adrenergic receptors, both of which are activated by epinephrine, but which can be differentiated by selective drugs, have opposite effects (inhibitory and stimulatory) on the adenylyl cyclase system.

Transgenic mice were created with cardiac - specific overexpression of the beta 2 - adrenergic receptor.

Major determinants of alpha 2 - and beta 2 - adrenergic receptor agonist and antagonist ligand binding specificity are contained within the seventh membrane spanning domain.

Enhanced myocardial function in transgenic mice overexpressing the beta 2 - adrenergic receptor

This lecture illustrates the early stages in the planning and discovery of propranolol, an adrenaline beta - adrenergic receptor antagonist, and cimetidine, a histamine H2 - receptor antagonist — the first examples of clinically useful drugs from each of these classes.

Beta - adrenergic mechanism of insulin - induced adrenocorticotropin release from the anterior pituitary

The insulin - induced stimulation of ACTH release was blocked in both the control and lesioned animals by prior treatment with either the beta - adrenergic antagonist propranolol or the glucocorticoid analog dexamethasone.

To demonstrate that receptors still function inside the nanodisc, Sligar's graduate student Andrew Leitz turned to a well - known protein: the β2 adrenergic receptor (β2AR), a target of heart drugs called beta blockers.

Partial activation of the yeast pheromone response pathway by beta - adrenergic receptor agonists was achieved in cells coexpressing h beta - AR and a mammalian G protein (Gs) alpha subunit - demonstrating that these components can couple to each other and to downstream effectors when expressed in yeast.

When this clone was inserted into a mammalian expression vector and transfected into COS - 7 cells, a protein that specifically phosphorylated the agonist - occupied form of the beta 2 - adrenergic receptor and phosphorylated, much more weakly, the light - bleached form of rhodopsin was expressed.

The functionality of the «desensitized» beta - adrenergic receptor was assessed by implanting purified beta - adrenergic receptor preparations from control and desensitized turkey erythrocytes into phospholipid mixtures and then fusing them with receptor - deficient cells (Xenopus laevis erythrocytes).

Desensitized beta - adrenergic receptors showed a 40 to 50 percent reduction in their ability to couple to the heterologous adenylate cyclase system, comparable to the reduction in their functionality observed in their original membrane environment.

The beta - adrenergic receptor kinase (beta - ARK), which specifically phosphorylates only the agonist - occupied form of the beta - adrenergic and closely related receptors, appears to be important in mediating rapid agonist - specific (homologous) desensitization.

Beta - adrenergic receptor kinase - 2 and beta - arrestin - 2 as mediators of odorant - induced desensitizaBeta - adrenergic receptor kinase - 2 and beta - arrestin - 2 as mediators of odorant - induced desensitizabeta - arrestin - 2 as mediators of odorant - induced desensitization

In the National Institutes of Health - funded study, researchers at Wake Forest Baptist identified and evaluated six rare gene variants within the beta2 - adrenergic receptor gene, the gene that may influence the response to beta agonist drugs.

Reciptrocal regulation of beta - adrenergic receptor mRNA stability by mitogen activated protein kinase activation and inhibition.

Phosphorylation of Src by phosphoinositide 3 - kinase regulates beta - adrenergic receptor - mediated EGFR transactivation.

Howard A. Rockman, M.D. Duke University Medical Center Novel molecular therapeutic strategies in heart failure: role of beta - adrenergic receptor desensitization

When the adrenal gland produces adrenaline and the adrenaline (beta - adrenergic) receptor communicates with the G - protein and its signal cascade, the parts of the body are alerted to the need for action; the heart beats faster, the blood flow to the gut decreases while the blood flow to the muscles increases and the production of glucose is stimulated.

Unless scientists develop beta - adrenergic stimulants which would be applied to brown fat only, there is a potential risk for the development of many negative cardiovascular side effects or drastic mood swings and disturbances which were experienced with clenbuterol and products containing ephedrine.

area menu of ones that affect the receptor sites in around the heart whether it's the beta blockers or the — these adrenergic receptor blockers that affect heart contractility, so there's a couple different ones there and again in the end, we want to get to the root cause of why you have these blood pressure issues to begin with.

Both groups also received traditional therapies, including corticosteroids and beta 2 adrenergic agonists.

These drugs may interact with insulin: anabolic steroids, alcohol, aspirin and other salicylates, beta - adrenergic blockers, cardiac glycosides, dextrothyroxine, dobutamine, epinephrine, estrogen / progesterone combinations, furosoemide, glucocorticoids, guanethidine, monoamine oxidase inhibitors, phenylbutazone, sulfinpyrazone, tetracycline, thyiazide diuretics and thyroid medications.

Some dogs may be treated with beta - adrenergic blockers (e.g. atenolol) either with or without the balloon valvuloplasty.

Salivary alpha amylase as marker for adrenergic activity during stress: Effect of beta blockade

Association between Depression, Pressure Pain Sensitivity, Stress and Autonomous Nervous System Function in Stable Ischemic Heart Disease: Impact of Beta - Adrenergic Receptor Blockade