Type 1 diabetes occurs due to
beta cell destruction resulting in an insulin deficiency which must be replaced by insulin injections.
Diabetes is due to the pancreatic
beta cell destruction, and the notion of making use of stem cells as a way of fixing this deficiency in individuals with diabetes is certainly not new.
«The goal of our work is to understand the cellular mechanisms responsible for
beta cell destruction so that we can identify the best targets for beta cell protection,» Costes said.
The patients also showed stabilization and even improvement in measures of insulin production after 12 weeks, suggesting that the therapy might arrest
beta cell destruction, the authors say.
Not exact matches
Type 1 diabetes, formerly known as juvenile diabetes, is characterized by the immune system's
destruction of the
beta cells in the pancreas.
This happens because the NKp46 receptor recognizes pancreatic
beta cells, leading to their
destruction.
In people with Type 2 diabetes, the process appears to not work properly, contributing to the
destruction of
beta cells.
Type 1 diabetes, which usually manifests during childhood, is caused by the
destruction of
beta -
cells (β -
cells).
Our overall goal is to prevent the autoimmune mediated
destruction of islet
beta cells.
Type I diabetes is characterized by insulin deficiency primarily caused by the autoimmune - mediated
destruction of insulin secreting
beta cells located in the pancreas.
Type 1 diabetes, which usually manifests during childhood, is caused by the
destruction of
beta -
cells (ß -
cells).
In mice, an injection of AAT can halt the
destruction of
beta cells, so doctors want to know if it will do the same in people, in a safe manner.
Killer T -
cells have previously been implicated as playing a major part in initiating this
destruction of
beta cells — however, it is as yet unclear what the triggers to this case of mistaken identity might be.
This may well improve insulin sensitivity and prevent the
destruction of the insulin - producing
beta cells of the pancreas.
Living with type 1.5 diabetes (a «slow - progressing» version of type 1 diabetes) means that your pancreas is still capable of producing insulin, however a weak autoimmune reaction targets
beta cells for
destruction over the course of time.
Type I diabetes mellitus (sometimes also called insulin - dependent diabetes mellitus) results from total or near - complete
destruction of the insulin - producing
beta cells.
This means that affected dogs need to take exogenous insulin for the rest of their life to control their blood glucose levels after the irreversible
destruction and functional loss of pancreas
beta cells has occurred.
While dogs tend to develop diabetes mellitus secondary to either immune
destruction of the pancreatic
beta cells or severe pancreatitis, cats tend to develop diabetes mellitus secondary to pancreatitis or amyloidosis.