Sentences with phrase «beta cell growth»

He is internationally recognized for his work with beta cell growth and regeneration, a topic that is critical to the treatment and cure of diabetes,» said George King, M.D., Chief Scientific Officer at Joslin Diabetes Center and Professor of Medicine at Harvard Medical School.

Scientists have been investigating molecular pathways that govern beta cell growth in hopes of finding new therapies that would help people regain blood glucose control after the onset of diabetes.

Not exact matches

Your baby's body uses the beta - carotene in sweet potatoes to make vitamin A, which is essential for cell growth, good vision and also has an * antioxidant effect.

What they discovered was that an inflammatory factor known as TGF - beta (transforming growth factor - beta) can give cancer cells properties of immune cells by supplying the surface of the cancer cell with a receptor that normally only exists on the white blood cells that travel through the lymphatic system.

Mutations in the beta subunits of these patients result in lower levels of hemoglobin and fewer red blood cells, causing severe anemia, poor growth and bone abnormalities.

However, tumors produce high amounts of a protein called Transforming Growth Factor - Beta (TGF - β) that suppresses the activity of NK cells.

However, when the tips of these blood cells begin to sprout, the thrombospondin - 1 proteins give way to TGF - beta 1 and periostin proteins in the neovasculature, turning it into a metastatic niche that not only permits but accelerates the growth of breast cancer cells.

«It turns out that the same signal — the so - called epidermal growth factor (EGF) pathway — control both the formation of pipes and beta cells through polarity changes.

A new study just published in the journal Glia and available online on July 11th, details the newly discovered mechanism by which astrocytes are involved in inhibitory synapse formation and presents strong evidence that Transforming Growth Factor Beta 1 (TGF β1), a protein produced by many cell types (including astrocytes) is a key player in this process.

Earlier laboratory studies had shown that fetal fibroblasts, closely related cells from the fetus, respond to tamoxifen by producing a natural peptide called transforming growth factor beta - 1 (TGF beta - 1).

Human transforming growth factor - beta complementary DNA sequence and expression in normal and transformed cells.

That defect may represent a previously unrecognized mechanism that aids in developing diabetes, Kahn says, as well as helping to explain the problems in wound healing, tissue repair and even beta - cell growth that are common among people with diabetes.

Complementing this work are recent advances at Joslin identifying new islet growth in patients with long - standing type 1 diabetes, as well as identifying potential islet growth factors, which occur in situations of insulin resistance, that could be used to stimulate the growth of the patient's own beta cells.

To better understand how insulin signaling affects beta - cell growth, the Joslin scientists next studied a pathway involving a protein called FOXM1.

Cell contact, prostaglandin E (2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - Cell contact, prostaglandin E (2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - 160.

Increased transforming growth factor beta expression inhibits cell proliferation in vitro, yet increases tumorigenicity and tumor growth of Meth A sarcoma cells.

He is internationally recognized for his work on the control of cell growth and fate by the TGF -(beta) family of growth factors.

Using blood collected from elderly persons aged up to one hundred and demonstrating no cognitive impairment, the researchers isolated precisely those immune cells whose antibodies are able to identify toxic beta - amyloid plaques but not the amyloid precursor protein that is present throughout the human body and that presumably plays an important role in the growth of nerve cells.

This leads to regulatory T - cell development, subsequent interleukin (IL)-10 and transforming growth factor beta secretion, and ultimate suppression of the immune response.

Transforming growth factor beta, TGFβ, acts as an anti-proliferative factor in epithelial cells.

«There's a lot of growth in beta cells up until puberty or even young adulthood, but after that, there's a very slow turnover,» she says.

Expression of mTert in primary murine cells links the growth - promoting effects of telomerase to transforming growth factor - beta signaling.

Reishi mushroom contains special polysaccharides called beta - glucans said to fight cancer cells by suppressing endothelial growth factor, support the immune system, and enhance cytotoxic receptors (NKG2D / NCR) killer cells.

When they leave the muscle cells FGF and IFG - 1 stimulate the satellite cells to start proliferating and differentiating, while the TGF - beta is in charge of mediating, in this case, inhibiting growth.

The sweet melon contains beta carotene, or vitamin A, which is believed to regulate the growth of skin cells on your scalp and sebum in the skin's outer layer, Dr. Zeichner says.

Your body breaks down beta - carotene into vitamin A, then uses it to support red blood cell growth, promote cell development and nourish your immune system.

At the same time, the protein Vascular Endothelial Growth Factor (VEGF) stimulates blood supply for the damaged tissue, Fibroblast Growth Factor - 2 (FGF - 2) stimulates the damaged cells to grow and reproduce themselves, Transforming Growth Factor - beta (TGF - beta) stimulates cartilage to grow, and Stem Cell Factor (SCF) stimulates your native inactive stem cells to become activated and assist in the repair of the damaged tissue.

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Reishi mushroom contains complex sugars known as beta - glucans that may stop the growth and prevent spread of cancer cells.

Red or orange vegetables and fruits are rich sources of beta - carotene which are effective in reducing the growth of estrogen receptor positive and negative breast tumor cells.