Sentences with phrase «beta cell progenitors»
Our therapy is based on the encapsulation and implantation of pancreatic beta cell progenitors (Pro-Islet-1) derived from human stem cells which secrete insulin in patients.
http://viacyte.com/
The Company's technology is based on pancreatic beta cell progenitors derived from human pluripotent stem cells.
Our therapy is based on pancreatic beta cell progenitors (Pro-Islet (TM)-RRB- derived from human pluripotent stem cells.
Not exact matches
«By identifying the signals that instruct mouse progenitor cells to become cells that make tubes and later insulin - producing beta cells, we can transfer this knowledge to human stem cells to more robustly make beta cells, says Professor and Head of Department Henrik Semb from the Novo Nordisk Foundation Center for Stem Cell Biology at the Faculty of Health and Medical Sciences.
It is a really amazing and simple mechanism, and by affecting the progenitor cells» so - called polarity we can control their conversion into beta cells», says Pia Nyeng.
But the extracted tissue began producing insulin, glucagon and other hormones after the newly identified cells were added, indicating that they were indeed progenitors capable of differentiating into all the islet cell types, including beta cells.
In addition, when these inhibitory progenitor cells were transplanted into apoE4 mice with an accumulation of amyloid beta, prior deficits were alleviated.
In the study, which was conducted in collaboration with researchers at UC San Francisco and published today in the Journal of Neuroscience, scientists transplanted inhibitory neuron progenitors — early - stage brain cells that have the capacity to develop into mature inhibitory neurons — into two mouse models of Alzheimer's disease, apoE4 or apoE4 with accumulation of amyloid beta, another major contributor to Alzheimer's.
The beta - catenin / TCF4 complex imposes a crypt progenitor phenotype on colorectal cancer cells.
The PEC - EnCap (formerly VC - 01 ™) product candidate delivers pancreatic progenitor cells in the Encaptra ® immunoprotective device, and is currently being evaluated in a Phase 1/2 trial in patients with type 1 diabetes who have minimal to no insulin - producing beta cell function.
The PEC - EnCap (formerly VC - 01 ™) product candidate delivers pancreatic progenitor cells in an immunoprotective device and is currently being evaluated in a Phase 1/2 trial in patients with type 1 diabetes who have minimal to no insulin - producing beta cell function.