STEP ONE is the first trial in the world investigating a stem cell - derived
beta cell replacement therapy for diabetes.
With these findings, Helmholtz Zentrum München scientists have discovered key molecular functions of stem cell differentiation which could be used for
beta cell replacement therapy in diabetes.
«JDRF remains dedicated to accelerating the delivery of
beta cell replacement therapies to the T1D community, and we commend ViaCyte in its announcement of the first patients to be implanted with the PEC - Direct islet cell replacement therapy,» said Derek Rapp, JDRF President and Chief Executive Officer.
Not exact matches
But in patients with type 1 diabetes,
beta -
cell replacement therapy is likely doomed to failure because the new
cells might fall victim to the same autoimmunity that destroyed the original
cells.
An EU - funded research project («HumEn»), in which Lickert and his team are participating, shall provide further insights in the field of
beta -
cell replacement therapy.
«The loss of insulin - producing
beta cells leads to type 1 diabetes, making it an ideal target for
cell replacement therapy,» said James Shapiro, MD, PhD, FRCSC, Director of the Clinical Islet Transplant Program, University of Alberta.
In addition, we use our expertise to facilitate the development of functionally mature
beta cells from embryonic stem
cells for
cell replacement therapies of type 1 diabetes.
Partial clinical hold on high dose SGT - 001 resolved, additional information requested on full clinical hold NIH grant will further development of
replacement beta cells for type 1 and type 2 diabetes New trial will assess MSCs to improve heart function in heart failure patients ReNeuron wins grant for retinal
cell therapy development
The VC - 01 product candidate is the first embryonic stem
cell - derived islet
replacement therapy to reach clinical testing and is currently being evaluated in patients with T1D who have minimal to no insulin - producing
beta cell function.