Sentences with phrase «beta cells in the lab»

Tests on human beta cells in the lab showed that the hormone had the same effect as in isolated rat beta cells.

Not exact matches

«There have been previous reports of other labs deriving beta cell types from stem cells, no other group has produced mature beta cells as suitable for use in patients,» he said.

But when the team instructed human beta - like cells grown in the lab to produce more ERRγ, «Voilà,» says Evans.

Looking back, under constant lab conditions, says Evans, grown beta cells were simply stuck in the fetal stage.

For example, in colorectal cancer lab models, where a mutation in the beta - catenin gene drives MYC to cancerous levels, eliminating PVT1 from these cells made the tumors nearly disappear.

The BYU team, comprised of graduate and undergraduate students in Tessem's lab and the labs of Ben Bikman and Jason Hansen (BYU professors of physiology and developmental biology), then dove in and dissected what was happening on the cellular level — specifically, the beta cell level.

To address the contribution of the GARP: TGF - beta axis to B cell biology, the Li lab generated two preclinical models: one in which GARP was overexpressed and one in which GARP expression was reduced.

In their lab, the researchers incubated certain amyloid beta fragments — referred to as Aβ (25 - 35)-- with cells (known as SH - SY5Y) often used in Parkinson's researcIn their lab, the researchers incubated certain amyloid beta fragments — referred to as Aβ (25 - 35)-- with cells (known as SH - SY5Y) often used in Parkinson's researcin Parkinson's research.

In a paper published online in Diabetes on January 26, biologists in the labs of Joslin Principal Investigator Rohit N. Kulkarni, M.D., Ph.D., and Anil Bhushan, Ph.D., at the University of California at Los Angeles used a genetic approach to show that a protein called cyclin D2 is needed for this beta - cell response in micIn a paper published online in Diabetes on January 26, biologists in the labs of Joslin Principal Investigator Rohit N. Kulkarni, M.D., Ph.D., and Anil Bhushan, Ph.D., at the University of California at Los Angeles used a genetic approach to show that a protein called cyclin D2 is needed for this beta - cell response in micin Diabetes on January 26, biologists in the labs of Joslin Principal Investigator Rohit N. Kulkarni, M.D., Ph.D., and Anil Bhushan, Ph.D., at the University of California at Los Angeles used a genetic approach to show that a protein called cyclin D2 is needed for this beta - cell response in micin the labs of Joslin Principal Investigator Rohit N. Kulkarni, M.D., Ph.D., and Anil Bhushan, Ph.D., at the University of California at Los Angeles used a genetic approach to show that a protein called cyclin D2 is needed for this beta - cell response in micin mice.

Spin out of Harvard U, which utilizes technology for manufacturing beta - cell therapeutic product for diabetes, developed in Doug Melton's lab.

Recent research of our lab and other groups has demonstrated that simultaneous deteriorations of both, number and function of insulin secreting beta cells are the cause of this shortage in insulin.

Back in 2011, for example, her lab demonstrated that beta cells in newborn rats are immature cells with very different gene expression and function than adult beta cells.

Chong Wee Liew, Ph.D., lead author and a postdoctoral researcher in the Kulkarni lab, first examined the expression of the tribbles protein in pancreatic islets (which house beta cells and other hormone - producing cells) in both humans and mice.

The result is the production of hundreds of millions of lab - produced human beta cells — able to relieve diabetes in mice.

The cell types involved in diabetes — the beta and immune cells — are being studied in the culture dish, as well as transplanted into lab animals.