Sentences with phrase «beta cells in the laboratory»

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Inclusion Criteria: • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 • Have histologically or cytologically confirmed advanced or metastatic non-small cell lung cancer (NSCLC)(Stage IIIb or greater) • Measurable disease, as defined by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 • Known PD - L1 tumor status as determined by an immunohistochemistry (IHC) assay performed by the central laboratory on tissue obtained at Screening • A woman of childbearing potential must have a negative highly sensitive serum (beta - human chorionic gonadotropin [beta - hCG]-RRB- at Screening within 14 days prior to study drug administration Inclusion Criteria for Crossover: • Participants must have been randomized to Arm A of the study and had radiographic disease progression according to RECIST 1.1 • Participants must have a mandatory biopsy at the time of disease progression according to RECIST 1.1 prior to crossing over.

The liposomes are made in the laboratory and designed to replicate the dying beta cells in the pancreas, which characterize type 1 diabetes.

Furthermore, because the TRG locus is rearranged before the TRB locus and these clonal rearrangements persist, even in alpha - beta T cells, laboratories testing for IGH, IGK and the TRG together are likely to detect at least one clonal biomarker target in the vast majority of hematologic malignancies.

Embryonic stem cells and iPS cells can be grown in large number in the laboratory and have the potential to be coaxed into becoming any cell type in the body, including glucose sensing, insulin - producing beta cells.

«It was surprising to discover that these neurons are involved not only in the control of the intake, which was already known, but also involved in the control of the amount of insulin secreted by the beta cells of the pancreas,» explains Zorzano, Head of the Laboratory of Complex Metabolic Diseases and Mitochondria at IRB Barcelona.