Sentences with phrase «beta cells work»

The new study, published in the Journal of Nutritional Biochemistry, finds beta cells work better and remain stronger with an increased presence of epicatechin monomers, compounds found naturally in cocoa.
Scientists from the Nencki Institute hope that understanding the cannabinoid pathway will enable to significantly extend beta cells working time.

Not exact matches

«Novel type 1 diabetes treatment shown to work on human beta cells transplanted into mice.»
Researchers studied the response of the insulin production to a meal to prove that the low level insulin production was coming from working beta cells.
«By understanding how stress accelerates invasion in aggressive breast tumor cells, this work will inform future studies into whether beta - blockers could be a useful adjuvant therapy in the treatment of some aggressive breast cancers.»
Working with cultures of respiratory tract cells, Elias's team found that the gene that codes for il - 6 is inactive unless a protein known as nf - kb (nuclear factor - kappa beta) attaches to the gene.
Richard A. Insel, M.D., chief scientific officer of the Juvenile Diabetes Research Foundation, a funder of Melton's work, said the «JDRF is thrilled with this advancement toward large scale production of mature, functional human beta cells by Dr. Melton and his team.
Little has been known about the ways in which many diabetes genes work, but a study published in the journal Cell sheds light on a genetic risk component of type 1 diabetes and a new approach for keeping beta cells strong.
In their work, the researchers also show how TGF - beta can be used in stem cell cultures to mass - produce nerve cells which in turn produce the signalling substance serotonin.
«The goal of our work is to understand the cellular mechanisms responsible for beta cell destruction so that we can identify the best targets for beta cell protection,» Costes said.
They found that mice that had beta cells in which autophagy didn't work properly showed elevated levels of toxic IAPP, which led to the death of the beta cells.
In people with Type 2 diabetes, the process appears to not work properly, contributing to the destruction of beta cells.
«Under no circumstances should it be concluded from our work that consumption of marijuana can be a way to cure diabetes,» Prof. Dobrzyn warns and explains: «The concentration of glucose in the blood is determined by the balance between the activities of alpha and beta cells of the pancreas and insulin target tissues such as skeletal muscle and adipose tissue.
Our lab and others have worked on the first problem and I am confident we will get buckets of beta cells.
The work highlights a previously unrecognized molecular pathway that contributes to the malfunction of insulin - producing pancreatic beta cells in T1D in human patients and in mice, and shows that a chemical intervention can help beta cells function properly and survive.
The ER is known to play a critical role in supporting the work of beta cells.
Work led by Dr. Blackwell is studying mechanisms that allow cells to maintain a «pluripotent» state that enables them to become a variety of cell types, including beta cells.
Complementing this work are recent advances at Joslin identifying new islet growth in patients with long - standing type 1 diabetes, as well as identifying potential islet growth factors, which occur in situations of insulin resistance, that could be used to stimulate the growth of the patient's own beta cells.
Better understanding of the beta - cell proliferation process eventually may lead toward therapies for diabetes patients, whose supplies of these cells often shrink over time, says Rohit Kulkarni, M.D., Ph.D., a Joslin Senior Investigator and senior author on a paper about the work published in the journal Cell Metabolcell proliferation process eventually may lead toward therapies for diabetes patients, whose supplies of these cells often shrink over time, says Rohit Kulkarni, M.D., Ph.D., a Joslin Senior Investigator and senior author on a paper about the work published in the journal Cell MetabolCell Metabolism.
He is internationally recognized for his work with beta cell growth and regeneration, a topic that is critical to the treatment and cure of diabetes,» said George King, M.D., Chief Scientific Officer at Joslin Diabetes Center and Professor of Medicine at Harvard Medical School.
In work reported in the journal PLoS One in June, the scientists compared healthy human beta cells from surgical donors with beta cells that had been transplanted into mice with suppressed immune systems.
Dr. Melton's lab has been working on getting «a molecular biography,» he said, of all the genetic steps required to make a stem cell a beta cell.
Our group is specifically working on improvement of islet isolation and transplantation protocols in clinical practice and the development of novel therapeutic options in the field of beta cell replacement with a clear translational «bench to bedside» approach by linking experimental research with preclinical and clinical work:
This would be really important if it worked in humans for type 2 diabetics that are slowly losing beta cells as the disease progresses.
He is internationally recognized for his work on the control of cell growth and fate by the TGF -(beta) family of growth factors.
In his work, he identified a robust method to create beta cells from stem cells, with the ultimate goal of using them to treat patients with diabetes.
«His work provides the foundation for the ultimate goal of transplantable, patient - specific beta cells
To understand gene regulation, Panne works on a cell - free model of the human interferon beta response to viral infection.
Her lab's most recent work, led by HMS Instructor Cristina Aguayo - Mazzucato, started instead with very old mice, created for another experiment, whose beta cells emitted fluorescent signals.
Renowned for our work in beta cell production and research, we are conducting studies to expand and boost insulin - producing cells and make them less susceptible to attack by the immune system.
In his project, Dr. Li is investigating whether beta blockers target T cells to control breast tumor development, and is also working to understand how this pathway regulates T cell responses to tumors, which may reveal novel targets for the immunotherapy of breast cancer.
Beta hydroxy acids work as an exfoliant, gently sloughing off the top layer of dead skin cells to make room for new ones.
If caught early, there's still enough beta cells and insulin production, so taking something like amla or whole food plant - based diet, exercise, etc, can bring the glucose down by allowing what insulin there is to work better, MUCH better in most cases.
However, this might not work with diabetics if the amount of animal fats and proteins are enough to keep them insulin resistant with fatty livers and somnolent beta cells since the increased carbohydrates will do a number on their blood sugar.
Beta - HD ™ Daily is specially formulated with Salicylic Acid to work with oily or congested skin to naturally soften sebum and dislodge dead skin cells.
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The beta cells just work better on some days than on others.
Salicylic acid is a beta - hydroxy acid that works by dissolving excess oil and gently exfoliating away dead skin cells.
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