Sentences with phrase «better animal models»

There's more to these findings than just lofty philosophical quandaries, though: If ravens really do possess a level of social cognition comparable to humans and other large primates, the birds might serve as better animal models to study this kind of behavior in the lab — which could help scientists understand why some humans are better at this kind of inference than others, and why some individuals can't manage it at all.

The UCSF TCORS also has two developmental projects — one on risk perceptions of smoking by older Americans, and another to develop better animal models of the cardiovascular effects of secondhand smoke and exposure to other tobacco products, said Glantz.

There is an urgent need for better animal models for laboratory research to study the Zika virus and potential treatments.

In the end, three companies formed to try to exploit CRISPR to create novel medicines, while Broad and two other companies licensed the technology to partners that hoped to engineer everything from improved crops and livestock to better animal models and industrial chemicals.

From accelerating the identification and validation of novel therapeutic targets, to creating better animal models of human diseases in a shorter time frame, to reducing the number of failed products, Crispr looks set to shave millions off R&D costs and boost drug discovery, she says.

Scientists believe having the hybrid embryos help them to create better animal models.

The key problem for research on smallpox is that there is no good animal model for the disease.

Understanding of the development of DPN is mostly obscure, partly due to the lack of good animal models available.

What is needed for a good animal model, and how are gene - snipping tools changing the game?

Herzberg said his stories dealt «with obviousness that is not obvious... the stethoscope as the eternal symbol of doctors, mice as our best animal model, eels as simple, almost boring, river fishes.

This anxious behavior mirrored that of CdLS patients, while autopsied brain tissue from individuals with CdLS showed symptoms of disease that matched those of the experimental mice suggesting that they were a good animal model.

«There hasn't been a good animal model for any kind of speech disorder,» says study author Wan - chun Liu, a senior research associate in Fernando Nottebohn's Laboratory of Animal Behavior.

Cultural stigma against diseases that some falsely believe to be weaknesses of character prevent people from coming forward for trials — a problem when there are no good animal models for diseases like depression and schizophrenia.

Wild H5N1 viruses can not latch on tothe cells in a person's nose and throat, but the mutant strains created by Fouchier and Kawaoka can spread between ferrets, which are viewed as a good animal model of flu transmission between humans.

«Now that we know more about why it's occurring, it might make it a better animal model.»

Here, we used Splenda as a means to test the combined effect of the commercial ingredients and used one of the best animal models of ileal Crohn's disease.»

Critics charge that rabbits are not good animal models for human brain diseases and note that the dialysis patients suffered from dialysis encephalopathy, or «dialysis dementia,» not Alzheimer's disease.

The loss was bad for the vaccine: In a series of experiments Hensley and his colleagues showed antibodies from humans and ferrets (a good animal model for influenza A studies) that had been exposed to the egg - grown vaccine did not effectively kill the circulating sugar - adorned viruses.

The finding, by researchers at the University of Illinois at Chicago College of Medicine, was reported July 16 at the Alzheimer's Association International Conference in Copenhagen by Mary Jo LaDu, who in 2012 developed a transgenic mouse that is now regarded as the best animal model of the human disease.

The project began in 2009 when Krasnow, frustrated by the lack of a good animal model for lung disease — his area of expertise — commissioned three high school interns to search the animal world for something better.

«The Medaka experiment finding of new genes affected by microgravity provides a good animal model to clarify this mechanism.»

Slicer touches on a very significant problem for glucosepane research: no good animal models.

«We have lots of good animal models in the laboratory that we can study.

Choosing the best animal model for every experiment is a cornerstone of the research approach taken by Davis Center scientists.

Furthermore, the heterozygous knock in mouse serves as a better animal model of the human disorder, as compared to the homozygous mouse, given that Huntington disease homozygosity is very rare in humans.

Not exact matches

[104] In place of WS, animal protectionists hold up their work with sheep producers of Marin County, California as a better coyote management model.

«What I've tried to do is create a sustainable organic farming model that is good for the earth, the soil, the animals, and the people working on these farms, and helps revitalize rural communities,» said Albert Straus, CEO and founder of Straus Family Creamery.

Their dinosaurs and animal models are by far the best I have come across in my almost 10 years of being a parent.

They then tested the contributions of samples from breast milk as well as individual molecules in both animal and cellular models of infection, measuring the length of time until resolution.

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

The CDC team's work combines «superb conventional epidemiology with a well - characterized animal model,» epidemiologists Barry Bloom and Peter Small write in an accompanying editorial.

Previously, animal models were all based on the early stage of metabolic dysfunction in the liver, which has allowed the development of good drugs for treating early - stage T2D.

And the enrichments may make the animals better at what they do: serving as important models for human disease.

The animals engage in more natural play behavior, Carlos says, and are better models for psychiatric disorders because they're not unnaturally depressed or anxious.

Stress can affect a wide range of physiologies and behaviors, and researchers are beginning to test whether the additions make the animals better models for depression — and, in the case of these particular fish — retinal regeneration.

As noted by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as humans point to the link between the gut microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the gut microbiome.»

A good model system for research is provided by Oesophagostomum dentatum, a roundworm which infects the large intestines of pigs, slowing the animals» growth and leading to significant economic losses.

Nadeau also studies the potential impacts of climate change on species around the globe, using modeling, field observation and experiments to predict where species are most vulnerable and determine how conservation groups can best mitigate the negative impacts of climate change on animal populations.

While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.

The study — which looked at the action of Substance P within nerve cells in the lab and in animal models — focused on acute pain, but Professor Gamper aims to look at its role within chronic pain as well.

Schmidt says, «These people can test compounds or antibodies in well - defined animal models that are representative of a human disease.»

Chief among the criticisms were the animal's hindlimbs, significantly smaller compared with other large predatory dinosaurs, as well as other researchers» theoretical Spinosaurus models.

They found that, for the same dataset, models that can better describe the data favour sponges at the root of the animal tree, while models that drastically fail to describe the data favour the comb jellies.

«But really, there is an opportunity with appropriate animal models to make a huge difference for the human community as well.»

«Most pain medications that have been tested in the past decade have failed in phase II human trials despite performing well in animal models,» notes Clifford Woolf, MD, PhD, director of Boston Children's F.M. Kirby Neurobiology Center and a co-senior investigator on the study with Michael Costigan, PhD.

To better determine the role of specific chemoattractants in type III hypersensitivity, lead author Yoshishige Miyabe, MD, PhD, a research fellow in Luster's lab, used multiphoton intravital microscopy — an imaging technology pioneered for studies of immune cell movements in living animals by CIID investigator and co-author Thorsten Mempel, MD, PhD — to follow in real time the development of IC - induced arthritis in a mouse model of rheumatoid arthritis.

The research showed that moral decisions in the con?ned scope of unavoidable traffic collisions can be explained well, and modeled, by a single value - of - life for every human, animal, or inanimate object.

«For that we needed these very carefully constructed, well - controlled animal models.

Researchers at the University of Minnesota have developed an animal research model for facioscapulohumeral muscular dystrophy (FSHD) to be used for muscle regeneration research as well as studies of the effectiveness of potential therapies for FSHD.

«There's a growing demand, as animal models aren't mirroring the diseases too well,» says David Dexter, director of the bank.