Given the similarity of these related proteins to one another, knowing the structure and mechanism of BRCC36 - KIAA0157 should enable researchers to
better model the structures of related complexes, and also probe their mechanisms.
Not exact matches
Starting with the
structure of the
model that you need helps keep you focused and will help you
better target the data you need to actually collect.
This desire to support and
better engage the municipal chambers in Greater Vancouver directly impacted the
structure of our new Membership
model.
The fundraising process can be grueling because experienced investors tend to ask numerous questions that likely have been posed to you before, questions that test your business
model and technology platform so all parties might realize the
best way of
structuring an investment.
'' Key differences and pros and cons between a term loan and a line of credit» Different pricing
models and loan
structures» How to choose the
best option for your business
«Because of the
structure of the industry, the opaqueness of the private - equity
model, the broadness of limited partnership agreements and the limited information rights of investors, we are perceiving violations despite the
best efforts of investors to monitor their investments,» Bowden said.
Territories that includes creating new social interaction
models, new roles as members of a social ecosystem, and advancing social business
models that may very
well alter the
structure and business operations they have been wedded to for decades — in ways they could not have dreamed of just a few short years ago.
Birch and Cobb maintain that the ecological
model is more adequate than the mechanical
model for explaining DNA, the cell, other biological subject matter (as
well as subatomic physics), because it holds that living things behave as they do only in interaction with other things which constitute their environment (LL 83) and because «the constituent elements of the
structure at each level (of an organism) operate in patterns of interconnectedness which are not mechanical» (LL 83).
A
model that is
well defined by effective procedures may be translated by the authority of Church's thesis into a Turing machine that captures the
structure of the
model.
Once we begin to think of our faith in terms of largeness instead of largess or in terms of measurable success or significant achievements or community stature or statistically significant gains or business
models or congregational
models or appropriate budget processes or cash flow direction or generally accepted accounting practices or independent audits or administrative requirements or managerial transparency or proper leadership roles and boundaries or membership trends or effective organizational
structures or a current and accurate vision statement — at that point, we have become the money changers — we have lost our faith and deserve to be driven away for we are neither living nor sharing the
Good News.
That's a
structure that a lot of the smaller clubs who are higher up in the table than we are — and playing
better football — that's the
model they employ.
The
best ownership
model for Arsenal will always include supporters being represented and involved in the ownership
structure as shareholders.
While the Carrier One bears many similarities to older Baby Björn
models with
well - padded shoulder straps and a comfortable waist band for distributing weight, note that Baby Björn really had to rethink the design of the soft -
structured carrier to pull off the ability to swing a child from front to back mode without the need for help.
«I loved that there was
structure to the program so it felt wholesome and safe and that the counselors were
well - trained and role
models for the kids.»
The new Bolivia is engaging in a process of in - depth institutional reforms, challenging mainstream narratives and political
structures and reinventing a
model of the state and creating notions of citizenship
better suited to highly diverse ethnic and cultural landscapes.
«Some companies may find that these
models work
best for them — but there are other routes that use existing Board
structures, complemented or supplemented by advisory councils or panels, to ensure all those with a stake in the company are properly represented.
To do so we drew the «ball - and - stick»
models of the atom positions using the
well - known
structure of the two crystals on either side of the interface and compared them with the images obtained with our microscope (which you can see on the background).
These
models utilize machine - learning techniques — the same ones used by companies like Netflix or Amazon that «learn» a customer's preferences and make recommendations based upon that data — in order to predict which chemical
structures are likely to have the
best overall CO2 absorption properties.
The research team developed a
model with
well - defined parameters, and included information about social
structure.
While mouse
models have traditionally been used in studying the genetic disorder, Deng said the animal
model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical
structure of the brain as
well as in the transmission of nerve impulses.
To
better understand the effect of a satellite on ring
structure, we plan to construct a new
model for the formation of Chariklo's rings.»
He also believes the technique will work reasonably
well for studying the
structure and function of proteins in most other
model organisms, including laboratory mice.
The team used an analytical
model to relate the variation in local mechanical properties to the changing dynamics of the
structure, which agreed fairly
well with the experimental dynamics tests.
Now that the researchers have the
structure of alpha - pinene, they are
better able to
model the first steps of nature's aerosol formation in the atmosphere.
Most
models try to identify cues from the words in the command as
well as the sentence
structure and then infer a desired action from that language.
More than three decades in the making, its elegant mathematical
structure was intended to replace the «standard
model», the eminently serviceable but sometimes creaky and in parts aesthetically unpleasing theoretical construct that is currently our
best description of matter's fundamental workings.
«The information collected using this technique can be used to
better understand the behavior of concrete when it fails, as
well as providing key data for «constitutive»
models that are used for designing and determining the safety of large - scale civil engineering
structures,» says Rahnuma Shahrin, a civil engineering Ph.D. student at NC State and lead author of a paper on the work.
Only 12,000 games were in the network developed for those tools, which proved to be useful but did not give a
good sense of the shape and
structure of the underlying
model, Wardrip - Fruin said.
To calculate which
model best describes the
structure of the Milky Way; the students then applied the Markov Chain Monte Carlo method.
These
structures and surfaces not only divert and channel the water, but provide different levels of friction that must be
modeled as
well.
You can always count on the weather... to ruin a perfectly
good game === Dr Norman Page says: September 14, 2013 at 8:12 am This new sensitivity estimate is merely a minimum tweak to a hopelessly faulty process.The climate
models are incorrectly
structured because they are based on three irrational and false assumptions.
«The point defects we investigated experimentally really correspond quite
well to the theoretical
model of potential defects», declared Dr. Galina Gurieva from the HZB
Structure and Dynamics of Energy Materials group.
To account for demographic differences that might impact social network
structure, our
model also included binary predictor variables indicating whether subjects in each dyad were of the same or different nationalities, ethnicities, and genders, as
well as a variable indicating the age difference between members of each dyad.
In late 2003, astronomers announced that the latest computer
models indicate that the
structure of a faint dust disk observed around Vega can be
best explained by the presence of Neptune - sized and Jupiter - sized planets orbiting at distances roughly similar to those held by their apparent «cousins» in the Solar System (more discussion below — ROE press release).
«We built several
models of equal quality from the photometric data, but we favored a
model made of two lobes since some of the
best adaptive optics observations suggest that the Trojan asteroid has a dual
structure,» said Josef Durech, co-author and researcher at the Charles University in Prague.
As mentioned in the previous section,
models that use «cold dark matter» of «WIMPs» provide the
best fit to the observed
structures.
She also played a key role in the accurate determination of two - and three - nucleon forces grounded in the fundamental theory of quantum chromodynamics, delivering an internationally widely adopted
model that provides a
good description of nuclear
structure and reaction properties of light nuclei.
Using myoblasts from DNM2 - mutated patients and using myoblasts and muscles from a knock - in mouse
model of DNM2 - related myopathy, we analyzed
structure of costameres by biochemical and immunocytochemical approaches, as
well as their ultrastructure.
Gene therapy restores vision - dependent behavior as
well as retinal
structure and function in a mouse
model of RPE65 Leber congenital amaurosis.
Together, this translational program is developed within the National Cancer and Cognition Platform (CNO / Ligue Nationale contre le cancer), with the aim to collaborate in a
structured way with French oncology groups, research teams as
well as pharmaceutical industry, by providing preclinical
models and guidance on standard operating procedures for ancillary or future studies in identified population at risk.
My research program is based on the love,
structure, honesty and directness that my heroes provided for me; this
model has served me
well as a mentor.
Structure and structure - function relationships are often better understood by introducing 3 - D reconstruction and advanced visualization and modelli
Structure and
structure - function relationships are often better understood by introducing 3 - D reconstruction and advanced visualization and modelli
structure - function relationships are often
better understood by introducing 3 - D reconstruction and advanced visualization and
modelling tools.
This gives a high level of flexibility for the search algorithm as
well, because both general (i.e. free rotation and translation) and more specific moves (i.e. adding a new
structure element to an existing
model in the membrane plane) are allowed and biased by probability.
For example, by using histone deacetylase (HDAC) inhibitors, which, by remodeling chromatin
structure, are thought to promote gene expression broadly, including for SMN2, numerous groups showed that they could increase SMN protein levels — both truncated and full - length — in mouse
models of SMA as
well as in patient - derived cell lines.
Some of the margins were razor thin and thus the group plans more
modeling of the
structure for a
better understanding of the wind load analysis.
Although it is
well established that the Sun's magnetic field is responsible for the supply of energy to the atmosphere, exactly how this magnetic energy is converted into thermal energy is still not understood in detail, as
models struggle to simultaneously encompass the very disparate temporal and spatial scales on which the heating has to occur, in different
structures, with a wide variety of characteristics (e.g. open versus closed
structures, short quiet - sun loops versus hot active - region loops and large - scale interconnecting loops).
It is not fully clear if this
model better reflects the neurological
structure of memory or an artifact related to the statistical interdependence of the immediate and delayed memory tasks within each sensory modality.
This long bob has been styled in super
structured curls at the bottom and sleekly parted down the middle at the top to show off the
model's jet black tresses in the
best way possible.
If you did want to lean into the comfortable look, the
model on the right does it
well by pairing them with more of a
structured shoe and jacket.
Miranda Kerr's stunning facial
structure, with high cheekbones and a perfectly symmetrical face that earned her a
well - deserved place among Australia's top
models, means that most hairstyles she chooses will look amazing!