Sentences with phrase «better models for human disease»

Cats and dogs that develop diseases like cancer naturally are often better models for human disease than lab rodents are, which is why more and more drug...

It now looks like many of these traits could be controlled by the combination of genes between different strains, thus producing mice that are better models for human disease.»

Not only can organoids potentially offer a better model for human disease, they can also be surprisingly easy to coax into being.

Not exact matches

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

With our human gut - on - a-chip, we can not only culture the normal gut microbiome for extended times, but we can also analyze contributions of pathogens, immune cells, and vascular and lymphatic endothelium, as well as model specific diseases to understand complex pathophysiological responses of the intestinal tract.»

And the enrichments may make the animals better at what they do: serving as important models for human disease.

For example, rats are often good models for humans in disease research, but they aren't when it comes to pooping because rats are pellet poopeFor example, rats are often good models for humans in disease research, but they aren't when it comes to pooping because rats are pellet poopefor humans in disease research, but they aren't when it comes to pooping because rats are pellet poopers.

Critics charge that rabbits are not good animal models for human brain diseases and note that the dialysis patients suffered from dialysis encephalopathy, or «dialysis dementia,» not Alzheimer's disease.

«These are strong evidence that cave fish could be a good model for human psychiatric disease.»

Overall, this work illustrates that better understanding the basic biology of the immune system in preclinical models may open up a window for the development of novel treatments for human autoimmune disease.

The researchers hope their study leads to better measures for modeling and predicting infectious disease transmission, but there are still open questions about the human - wildlife interface of disease.

Investigating mouse models for biological for research The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

This webinar will discuss the promise CRISPR / Cas9 has for rodent studies along with strategies for developing better models to understand and treat human disease.

These mice will be preserved in repositories and made available to the scientific community representing a valuable resource for basic scientific research as well as generating new models for human diseases.

«Ultimately, we have to get a human model for human diseases so that we can expand human experimental biology in an ethical way and ensure that better, safer drugs get to patients faster,» he says.

He later combined it with studies on chromatin, tissue specific gene expression and mouse models for human diseases including Type II diabetes, polycystic kidney disease as well as cancer.

The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

The BAC (Bacterial Artificial Chromosome) mouse model of Huntington's disease expresses the full length human htt transgene and has been well - characterized for its progressively impaired motor function.

Although the mouse remains the most cost - effective choice for comprehensive phenotyping, the rat remains a better model for a number of human conditions, including cardiovascular disease, diabetes and behavioral disorders.

Fruit flies serve as a good model organism for understanding the molecular mechanisms behind many human diseases — around 75 percent of disease - causing genes are found in the species in a similar form.

«With the idea to develop a mouse model for the rare human disease ALD, we reached out to genOway to help us in finding the best approach for this project.

Gage and Ghosh discuss how human skin cells induced to return to an immature state («induced pluripotent stem cells» or IPS cells) are revolutionizing our understanding and treatment of mental and neurodegenerative disorders, such as Parkinson's disease, as well as leading to new models of drug development for all diseases.

For three years now we have been working on human cell models of rare neurodegenerative diseases with special emphasis on neuroacanthocytosis, neuronal ceroid lipofuscinosis as well as motor neuron degeneration (using iPS cells).

«Infectious disease can mean making trade - offs between the risks and rewards of meeting others,» says Eli Fenichel, Arizona State University assistant professor and co-organizer of a transdisciplinary working group at NIMBioS that has developed a better model for understanding the role human decisons play in the spread of disease.

The emphasis is on developing intellectual abilities and research skills through investigations of infectious diseases of food - producing, companion, and aquatic animals, as well as animal models for human disease.

These mutations establish CMR as a novel animal model for Best macular dystrophy (BMD) in humans, an autosomal dominant, childhood retinal disease also caused by mutations in the Bestrophin gene [76, 77].