Sentences with phrase «between endoplasmic»
His laboratory currently applies high throughput imaging technologies to study trafficking between the endoplasmic reticulum and Golgi complex, and the internalization pathways taken by synthetic nanoparticles on exposure to cells.
http://www.sciencemag.org/ Not exact matches
An international group of researchers led by Professor Christoph Hess from the Department of Biomedicine at the University of Basel and University Hospital Basel have now found a structure that accounts for the rapid immunologic memory of particular immune cells (CD8 + memory T cells): these important memory cells form multiple connections between mitochondria — the powerhouses of cells — and the endoplasmic reticulum, the site of protein production.
They counted each of the contact points between two cellular organelles — the endoplasmic reticulum (ER) and mitochondria — and demonstrated for the first time that the number of these connections, called MAMs, markedly increase during obesity.
Thus, our study shows that membrane exchange between the early endocytic and the biosynthetic / secretory pathways involves specific components of the Rab and SNARE machinery, and suggests that retrograde transport between early / recycling endosomes and the endoplasmic reticulum is critically dependent on the sequential action of two members of the Rab6 subfamily.