The researchers acknowledge that using brain scans to study human cognition has its limitations because it relies on certain assumptions about the
links between brain regions and their functions.
In intelligent persons, certain brain regions are more strongly involved in the flow of
information between brain regions, while other brain regions are less engaged.
The lengths and strengths of the
connections between brain regions was used to estimate the network efficiency, a measure of how well each region is connected to other regions.
«Attention deficit disorders could stem from impaired brain coordination: Researchers uncover link absent
between brain regions in attention deficit hyperactivity disorder, schizophrenia.»
Task - based functional connectivity measures the synchronization of activation levels
between brain regions during the performance of a given cognitive task.
«Attention deficit disorders could stem from impaired brain coordination: Researchers uncover link
absent between brain regions in attention deficit hyperactivity disorder, schizophrenia.»
His work suggests that deep - brain stimulation — whether electrical or optical — may be most effective when it targets not the neurons themselves but the connections between cells, thereby affecting the flow of
activity between brain regions.
In a current study, brain researcher Georg S. Kanz of the University Clinic for Psychiatry and Psychotherapy of the MedUni Vienna was able to demonstrate that the very personal gender identity of every human being is reflected and verifiable in the
cross-links between brain regions.
The Times later published a letter signed by 45 neuroscientists explaining that «there is rarely a one - to - one
mapping between any brain region and a single mental state.»
In this study, led by Professor Zafar Bashir from Bristol's School of Physiology and Pharmacology, the researchers studied neurotransmitters, called glutamate and dopamine, which work together in controlling normal transmission
between these brain regions by communicating chemical information throughout our brain and are disrupted in schizophrenics.
For instance, knowing if there is a simple increase or decrease in connectivity
between brain regions compared to healthy individuals, or whether those with autism use entirely different brain regions to implement cognitive flexibility will enable researchers to better design interventions to improve cognitive flexibility skills.
Spindle neurons consist of a very large bipolar neuron that is found only in the frontoinsular and anterior cingulate cortex and thought to provide the
interconnection between brain regions that are activated by social learning.
The researchers were attempting to look at the brain's so - called «functional connectivity,» that is,
interactions between brain regions during the course of a particular task, or at rest, Laird said.
Next, the resting participants underwent two scans with another fMRI method known as blood oxygen level — dependent, or BOLD, to track connections and apparent information
flow between brain regions.
Participants were screened for risk - taking behaviors, such as drug and alcohol use, sexual promiscuity, and physical violence and underwent functional MRI (fMRI) scans to examine communication
between brain regions associated with the emotional - regulation network.
Data sharing has become increasingly urgent in neuroscience, with its diversity of research tools and the vast amounts of information they generate, both on the whole brain and on the connecting neural
circuits between brain regions.
«The cortical folding pattern itself may not be so important, but the disturbances in connections
between brain regions implicated by the changes in cortical folding could provide critical clues to deficits in the integrity of brain circuits that contribute to symptoms and functional impairment in schizophrenia,» commented Dr. John Krystal, Editor of Biological Psychiatry.
«There's not a one - to - one
correspondence between brain regions and behavior,» Phelps, director of the Phelps Lab at N.Y.U.'s Center for Neuroeconomics, said during a recent panel discussion on the issue.
«Our goal is to use some of the techniques we've developed in these papers to map patterns of dysfunction in individual patients, and then use those maps to guide interventions to restore normal
communication between brain regions.»
Interestingly, the researchers found that the degree of functional connectivity,
between brain regions involved in detecting grammatical violations and those related to working memory, predicted the performance accuracy of the participants in determining whether a sequence was grammatical or not.
This is so because brain regions are typically engaged by many mental states, and thus a one - to - one
mapping between a brain region and a mental state is not possible.»
Phineas Gage, the man whose personality changed drastically after an accident where an iron spike was driven through his head, is a famous early example of the
link between brain regions and behavior.
«As a dysfunction in the ability of the brain to regulate the communication of
information between brain regions,» Khambhati said, «seizures can be thought of as a traffic flow problem.
Neuroimaging methods provide a powerful tool to investigate brain connectivity, and have been widely applied to study the mutual relationship between structural and functional
connections between brain regions in healthy subjects and in patients.
Understanding the networks of connections
between brain regions — as depicted in this image — and how they are changed by a stroke is crucial to understanding how stroke patients heal, according to new research from Washington University School of Medicine in St. Louis.
The efficiency of brain networks was defined by the researchers in terms of the strength and direction of connections, or edges,
between brain regions of interest, or nodes.
The implant exploits the fact that even when the neural connection
between a brain region and the muscles it controls is severed or damaged by, say, a stroke or spinal injury, the controlling neurons remain active.
He used functional magnetic resonance imaging (fMRI), a means of measuring brain activity by detecting blood flow changes inside the brain, to measure differences in the strengths of communications
between brain regions.
Breaking communication
between the brain regions may interfere with tagging and subsequently handicap long - term memory.
Neuroscientist Jason Cooperrider and colleagues scanned Grandin's brain using three different methods: high - resolution magnetic resonance imaging (MRI), which captures the structure of the brain; diffusion tensor imaging (DTI), a method to trace the connections
between brain regions; and functional MRI, which indicates brain activity.
New research begins to demystify communication
between brain regions, potentially paving the way to treating disorders caused by crossed signals
A new study published in the current issue of Biological Psychiatry suggests that schizophrenia is associated with reductions in the complexity of the cortical folding pattern that may reflect deficits in the structural connections
between brain regions.
«But genes tied to autism tend to affect specific functions, such as the connections
between brain regions that are essential to many human - specific behaviors, like speech and language.»
While the NIH project attempts to map the large - scale connections
between brain regions, some scientists want to pry deeper: They aspire to eventually map the human brain neuron by neuron, constructing a full «wiring diagram» of our most complex tissue at its most fine - grained.
Researchers didn't find a link
between this brain region and memory deficits in people with Alzheimer's disease, only in those without any diagnosis of cognitive decline.