Sentences with phrase «between cadherins»
As a doctoral student in the lab of Drs. Margaret Wheelock and Keith Johnson at the University of Toledo, Dr. Islam focused on identifying a link between cadherins (a family of cell adhesion proteins) and tumorigenesis (start of cancer cell formation).
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The accumulation of different amounts of cadherins produced different levels of adhesiveness between cell junctions, resulting in a mosaic pattern.
Through further testing, they figured out that when Notch1 is activated and its intracellular domain is released, its TMD assembles a complex in the membrane with the proteins VE - cadherin, Rac1, LAR, and Trio, which collectively assemble and maintain the adherens junctions between cells and distribute actin fibers against the cell membrane to support those junctions.
«So we were able to show a complete correlation between miR - 200 and E - cadherin / Vimentin expression,» Peter added.
Dynamics between actin and the VE - cadherin / catenin complex: novel aspects of the ARP2 / 3 complex in regulation of endothelial junctions.