Sentences with phrase «between cells in a tissue»

ECM is the fibrous material between cells in tissues like skin, cartilage, or tendon that gives them their strength, stretchiness, squishiness, and other mechanical properties.

Not exact matches

Whilst acknowledging that many questions remain unanswered in the debate between those who would advocate the use of stem cells taken from human embryos, and those experimenting on stem cells drawn from tissues of the adult human body, there is a lengthy discussion of the moral status of the human embryo as being a crucial matter in this regard.
Milk ducts found between fat cells and the glandular tissue also grow in number and size creating a complex web of pathways throughout your breast leading to your nipples.
The researchers thought this ability to switch between different cell types could explain why they can spread so easily around the body; switching cell type effectively disguises the cells in different tissues.
Stomach switch The key to turning pluripotent stem cells into stomach cells was a pathway of interactions that acts as a switch between growing tissues in the intestine and in the antrum, a part of the stomach near its outlet to the small intestine.
Balls of brain tissue generated from stem cells are enabling us to understand the underlying differences between people who struggle to be sociable and those who have difficulty reining themselves in.
Until now, there was no knowledge about a potential correlation between the classification of the inflammatory cells in the airways and the lung tissues
To address this gap in knowledge, Mirabello and Schiffman teamed up with co-senior author Robert Burk of Albert Einstein College of Medicine to sequence the whole genomes of 5,570 HPV16 - infected cell and tissue samples from women around the world and to identify associations between HPV16 genetic variants and the risk of cervical precancer and cancer.
The body's tissue is full of small gaps in between the different proteins and cells that make it up.
Recent studies suggest that the total loss in brain volume due to atrophy — a wasting away of tissue caused by cell degeneration — between our teen years and old age is 15 percent or more, which means that by the time we're in our seventies, our brains have shrunk to the size they were when we were between 2 and 3 years old.
«Our studies imply that the change of oxygen levels in different tissues can be sensed by Treg cells and that this process is critically important for maintaining the correct balance between activation and suppression of the immune system,» says Liu.
«It is rather remarkable that the difference between cancers with bad outcomes and good outcomes is found not in the malignant cells, but in the tissue adjacent to the cancer.
Plakoglobin is a component of two important structures involved in cell - to - cell adhesion, and the investigators found that suppressing its expression caused CTC clusters to fall apart, reducing their metastatic potential, and also disrupted cell - to - cell contact between breast cancer cells but not normal breast tissue.
They also applied it to human brain tissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtissue collected by the Genotype - Tissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subTissue Expression (GTEx) Project, finding that they could a) identify expression signatures unique to neurons, glial cells, and other cell types in the brain (including rare types), and b) differentiate between closely related cell subtypes.
«High concordance between EGFR mutations from circulating - free tumor DNA and tumor tissue in non-small cell lung cancer.»
«This is a unique platform to study interactions between drugs and cells or tissues, specifically in the kidney, where current models were lacking,» said Sakolish.
To unravel the complex signaling pathway map, the scientists used their own findings from the analysis of factors regulated up or down in the interplay between tissue and stem cells, linking them with the signaling pathways described in existing literature.
«We suspect this communication system between adipose tissue and liver may have evolved to help fat cells command the liver to supply the body with glucose in times of nutrient deprivation.
This switch is accompanied by a complex communication process between the stem cells and tissue cells — an area that had not previously been examined in any depth.
«Under no circumstances should it be concluded from our work that consumption of marijuana can be a way to cure diabetes,» Prof. Dobrzyn warns and explains: «The concentration of glucose in the blood is determined by the balance between the activities of alpha and beta cells of the pancreas and insulin target tissues such as skeletal muscle and adipose tissue.
«Understanding how the drug also enables crosstalk between fat cells and the liver in obese mice allows us to see more of the amlexanox picture — and also sheds light on communication between different tissues in the body.»
Interleukin - 33 (IL - 33), discovered in 2003 by Jean - Philippe Girard's team, is a protein in the family of interleukins, soluble messengers that enable communication between cells in the immune system and play a crucial role in tissue inflammation.
The team report a molecule called lysophosphatidic acid (LPA) changes cells from a solid - like to a liquid - like state, allowing cells to flow between normal tissues in the body.
Now, in a study recently published in the journal PLOS ONE, a team of scientists from VCU Massey Cancer Center have shown a genetic relationship between the reactivation of hCMV and the onset of graft - versus - host disease (GVHD), a potentially deadly condition in which the immune system attacks healthy tissue following a bone marrow or stem cell transplant.
In normal cells, this is a part of the wound repair process when PGE2 induces tissues stem cells to regrow; in cancer PGE2 ironically induces regrowth of more cancer stem cells in between chemotherapy cycles, Kurtova and Xiao saiIn normal cells, this is a part of the wound repair process when PGE2 induces tissues stem cells to regrow; in cancer PGE2 ironically induces regrowth of more cancer stem cells in between chemotherapy cycles, Kurtova and Xiao saiin cancer PGE2 ironically induces regrowth of more cancer stem cells in between chemotherapy cycles, Kurtova and Xiao saiin between chemotherapy cycles, Kurtova and Xiao said.
«The cancer stem cells actively regrow and respond to the induced damage or apoptosis (cell death) caused by chemotherapy in between the different cycles, similar to how normal tissue stem cells respond to wound - induced damages.»
In a study published in the Journal of Clinical Investigation, researchers looked at how immune cells reached the myelin, focusing on the barrier between brain tissue and the rest of the bodIn a study published in the Journal of Clinical Investigation, researchers looked at how immune cells reached the myelin, focusing on the barrier between brain tissue and the rest of the bodin the Journal of Clinical Investigation, researchers looked at how immune cells reached the myelin, focusing on the barrier between brain tissue and the rest of the body.
Surgeons will monitor a traffic light - like video display as they cut, he explains, with red indicating tumor cells, green healthy tissue, and yellow something in between.
In an elegant proof - of - principle approach, the researchers used synthetic molecules to decrease the physical distance between the ER and mitochondria in cells and in liver tissue and found that this intervention impaired mitochondrial function and made mice more sensitive to high fat diet - induced insulin resistance and diabeteIn an elegant proof - of - principle approach, the researchers used synthetic molecules to decrease the physical distance between the ER and mitochondria in cells and in liver tissue and found that this intervention impaired mitochondrial function and made mice more sensitive to high fat diet - induced insulin resistance and diabetein cells and in liver tissue and found that this intervention impaired mitochondrial function and made mice more sensitive to high fat diet - induced insulin resistance and diabetein liver tissue and found that this intervention impaired mitochondrial function and made mice more sensitive to high fat diet - induced insulin resistance and diabetes.
Some possibilities include the ready availability of quick energy in the stored fat, or the fact that the fat may provide an accessible source of lipid - based signaling molecules to facilitate communication between cells or tissues.
The transplanted stem cells had differentiated into endothelial cells — which form the inner lining of a blood vessel, providing a barrier between blood and spinal cord tissue — and attached to capillaries in the spinal cord.
The results show that generation of an optimal immune response to cancer requires cooperation between two types of memory T cell — one circulating in the blood and the other resident in tissues — that can be reactivated with current immunotherapy strategies.
The Arizona researchers studied whether cage conditions affect mice with one copy of a gene called fibulin - 4, a member of a family of genes believed to code for proteins that stabilize the connective tissue found between cells in arteries and other blood vessels.
The bond between either cells and other cells or cells and surfaces is vital to organisms, for example in the development of internal organs and tissue.
Using miR - 192 levels in the cells, the investigators were able to differentiate with very high certainty between normal and chronically inflamed pancreas tissue as well as between healthy pancreas tissue and pancreatic cancer.
The remaining gaps between natural and bioengineered tissues may come from different developmental cues caused by the unique microenvironment of cells developing in a petri dish versus that of cells developing in a person or animal.
In muscle tissue, we observed only rare F4 / 80 - expressing cells between myofibrils.
He wants to know how the interplay of structural, chemical, and electrical signals in and between cells of nervous tissue gives rise to behavior.
In addition, some of the most important interactions between innate immune cells and these pathogens occur in the tissue and not in peripheral blood, which by necessity is the compartment on which most HIV and TB research is baseIn addition, some of the most important interactions between innate immune cells and these pathogens occur in the tissue and not in peripheral blood, which by necessity is the compartment on which most HIV and TB research is basein the tissue and not in peripheral blood, which by necessity is the compartment on which most HIV and TB research is basein peripheral blood, which by necessity is the compartment on which most HIV and TB research is based.
The relationship between stromal cell derived SPARC in human gastric cancer tissue and its clinicopathologic significance.
Advanced Regen Medical Technologies, LLC — Dedicated to making advances in restoring function to stem cells of aged patients, the company focuses on the association between aging and the loss of our body's inherent ability to maintain and repair tissue.
They found a strong correlation between cancer incidence and the number of times the stem cells in the tissues divide.
We will combine methods from the fields of immunology, developmental biology and angiogenesis to understand in vivo the development and lineage - specific function (s) of resident macrophages, thereby opening new venues of research into the interaction between macrophages and endothelial cells in response to tissue damage.
Similarity between the osteoblasts and the calicoblastic epithelium cells of scleractinian coral was also shown in the localization of the protein BMP in the tissue of S. pistillata (Zoccola et al., 2009), and for its role in the coral biomineralization (Mass et al., 2016; Zoccola et al., 2009).
The relationship between cancer and embryonic tissues was first proposed in the 1870s by Francesco Durante and Julius Cohnheim, who thought that cancers originated from cells in adults that persist in an immature, embryonic - like state.
Chief among them was the finding that in all placental mammals FOXP3 acts through a snippet of DNA called the CNS1 enhancer to trigger the formation of a cohort of Tregs designated «peripheral» (whereas most Tregs are produced in the thymus gland, which sits between the lungs, a subset of the cells act as sentinels suppressing runaway immune responses in the body's peripheral tissues).
A disparity between these cell types, when there are too many Th17 and not enough Tregs, can lead to a hyperactive immune system, resulting in inflammation, tissue damage, and autoimmune disease.
We are using a new technique, called single cell RNA sequencing, to isolate thousands of single neurons from human brain tissue, study all the genes that are expressed in each individual cell, and make cell - to - cell comparisons between normal, early stage and late stage AD.
According to the grant's description, «the communication required to establish the symbiosis between two widely different species occurs between cell layers in tissues, between organs in the plant, and across a time span from hours to days.»
A wound - healer run amok In the 1970s, a scientist at the University of Geneva in Switzerland discovered cells in healing wounds that seemed to be intermediate in character between fibroblasts, which secrete fibers such as collagen that make up the matrix that holds cells together in tissues, and smooth muscle cells, like those in the intestines and blood vesselIn the 1970s, a scientist at the University of Geneva in Switzerland discovered cells in healing wounds that seemed to be intermediate in character between fibroblasts, which secrete fibers such as collagen that make up the matrix that holds cells together in tissues, and smooth muscle cells, like those in the intestines and blood vesselin Switzerland discovered cells in healing wounds that seemed to be intermediate in character between fibroblasts, which secrete fibers such as collagen that make up the matrix that holds cells together in tissues, and smooth muscle cells, like those in the intestines and blood vesselin healing wounds that seemed to be intermediate in character between fibroblasts, which secrete fibers such as collagen that make up the matrix that holds cells together in tissues, and smooth muscle cells, like those in the intestines and blood vesselin character between fibroblasts, which secrete fibers such as collagen that make up the matrix that holds cells together in tissues, and smooth muscle cells, like those in the intestines and blood vesselin tissues, and smooth muscle cells, like those in the intestines and blood vesselin the intestines and blood vessels.
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