Sentences with phrase «between circadian clocks»

A possible link between circadian clocks, regulation of glucose metabolism, and melatonin signaling in the pancreas was indicated by genetic studies (255).

Intriguingly, recent studies have also found a link between circadian clocks and metabolism.

«Studies strongly suggest a link between circadian clocks, insulin resistance and diabetes development,» explains Charna Dibner, the co-director of the study.

Overall, these studies suggest that misalignment between the circadian clock and social rhythms and between sex - dependent biological factors such as body composition and gender - dependent social timing impact pathogenesis of diabetes in men and women.

«We are currently working to identify the relationship between the circadian clock, metabolism and the immune system, so that one day we could develop therapies to treat diseases influenced by circadian clock disruption — including not only obesity and diabetes, but also potentially multiple sclerosis and even Alzheimer's disease.»

To study the precise relationship between the circadian clock, light and metabolism, Rust and his colleagues created genetically engineered cyanobacteria that were able to feed on sugar in addition to normal photosynthesis.

Nothing good, say scientists exploring what appears to be a direct connection between a circadian clock that isn't working as it should and an enzyme that promotes inflammation working overtime.

These results provide additional evidence, from human populations, for a genetic relation between the circadian clock system and metabolic function and the risk of metabolic diseases.

Not exact matches

According to the American Academy of Pediatrics, an infant typically sleeps between 16 to 18 hours a day — and sleep patterns are erratic since newborns do not yet have an internal biological clock or circadian rhythm.

Determining the differences between short and normal period clocks in spiders may help researchers find out why and how different circadian clocks are suited to the particular environmental challenges of each species, Moore said.

Our sleep - wake cycle, or circadian rhythm, is the result of a complex balance between states of alertness and sleepiness regulated by a part of the brain called Suprachiasmatic Nucleus (SNC); in puberty, shifts in our body clocks push optimal sleep later into the evening, making it extremely difficult for most teenagers to fall asleep before 11.00 pm.

Circadian rhythm explains why, when there is a temporary mismatch between our external environment and our internal biological clocks — like when we travel across several time zones — humans experience «jet lag.»

Jet lag is known for its fatigue - inducing effects, most of which stem from a mismatch between a person's internal clock and the time zone he or she is in, something called «circadian misalignment.»

«This year's Nobel Laureates have been studying this fundamental problem and solved the mystery of how an inner clock in most of our cells in our bodies can anticipate daily fluctuations between night and day to optimize our behavior and physiology... since the paradigm shifting discoveries by Hall, Rosbash and Young, circadian biology has developed into a highly dynamic research field with vast implications for our health and well - being.»

With her HHMI money, she will explore the connections between the immune system and circadian clock genes, as well as the link between immune response and DNA repair genes.

«We know that night time shift workers are more likely to suffer health problems due to disruption of their circadian clock, and the mismatch between the timing of the clock and their sleep - wake cycle.

His lab, the largest at the Buck, has diverse projects underway, including: understanding the link between aging and nutrients, gut function, calcification, circadian clocks and diabetic complications.

Since these findings uncovered a link between p75NTR and metabolism, the research team tested — first in a petri dish and then in animal models — whether there was also a link between p75NTR and the circadian clock.

«In 2015, we had reported the synthesis of a molecule with demonstrated period - shortening activities on mammalian circadian clocks discovered through a collaboration between ITbM's chronobiologists, synthetic chemists and theoretical scientists,» says Yoshimura.

The connection appears to be between Bmal1, a transcription factor that senses light and drives our master circadian clock, and ADAM17, an enzyme that sets inflammation - producing proteins free from our cells to target and thicken our blood vessel walls.

There's a positive association between physical activity and genes that affect your circadian clock.

These findings demonstrate that the adipocyte circadian clock acts at the interface between the central nervous system and the predominant peripheral energy storage tissue to coordinate the temporal organization of feeding behavior and maintain energy balance.

In human populations, genome - wide association studies have revealed associations between variants of the circadian clock — related gene Mntr1b, which encodes melatonin receptor 1B, fasting glucose concentrations, and the risk of type 2 diabetes (12 — 14).

In the case of jet lag, circadian rhythms become out of sync with the time of day when people fly to a different time zone, creating a mismatch between their internal clock and the actual clock.