Meta - analyses examining the relationship
between coffee intake and risk of coronary heart disease have observed a positive association among case - control studies but not among prospective cohort studies.1, 2 According to the most recent meta - analysis, 1 the pooled case - control data show a 60 % increased risk for drinking 5 cups / d.
The data suggest a strong inverse association
between coffee intake and risk of suicide.
Conclusions: The data suggest a strong inverse association
between coffee intake and risk of suicide.
In 2016, the International Agency for Research on Cancer (IARC) reviewed all available research on coffee and cancer, including research published since its original review in 1991, and found no clear association
between coffee intake and cancer at any body site and, in some cases, found evidence that coffee drinking is associated with a reduced occurrence of certain cancers1.
The association
between coffee intake at study enrollment and risk of PD remained statistically significant for men whose diagnosis of PD occurred before (P =.005) and after 1991 (P =.01).
Although 2 retrospective studies found that persons with PD were less likely to be coffee drinkers than persons without PD, the results were not statistically significant.7, 8 In 2 other case - control studies, individuals with PD consumed significantly less coffee prior to the diagnosis of PD than controls.6, 19 In both studies, a significant inverse dose - response relationship
between coffee intake and PD was observed.
Whereas no statistically significant associations
between coffee intake ≥ 1 cup / d and reproductive hormones for whites and blacks were found, Asian women who consumed ≥ 1 cup coffee / d had elevated free (and total) E2 concentrations (free E2: β = 0.26; 95 % CI: 0.07, 0.44)(Table 2).
In 2016 the International Agency for Research on Cancer (IARC) reviewed all available scientific evidence and found no clear association
between coffee intake and cancer at any body site, including the stomach31.
A 2012 meta - analysis of 10 studies suggested an overall association
between coffee intake in increasing the risk of fractures, especially for women5.
A positive association was found
between coffee intake and pancreatic cancer in case - control studies that did not adjust for smoking.
Not exact matches
Three groups were identified — those consuming less than five percent of their total energy
intake in the morning (skipped breakfast and only had
coffee, juice or other non-alcoholic beverages); those consuming more than 20 percent of their total energy
intake in the morning (breakfast consumers); and those consuming
between five and 20 percent (low - energy breakfast consumers).
Despite the consistency of results across studies, time periods and populations, it is difficult to establish whether the association
between coffee drinking and HCC is causal, or if this relationship may be partially attributable to the fact that patients with liver and digestive diseases often voluntarily reduce their
coffee intake.
The researchers explained that despite the fact that caffeine
intake is strongly related to smoking and has been proven to increase risk of preterm delivery as well as the baby being small for gestational age at birth, in this study they found no link
between either
coffee caffeine or total caffeine and preterm delivery, however they did find a connection
between caffeine and being small for gestational age.
This is because most studies assess
coffee intake without distinguishing
between regular and decaf
coffee, and some don't even include decaf
coffee.
Background: Several studies have linked
coffee intake and smoking to foetal death, but a possible interaction
between both exposures remains unknown.
The authors found association
between total caffeine
intake (through
coffee, tea, and dietary caffeine) and general cognitive ability and memory.
A general survey performed in Taiwan found that among all lifestyle factors examined, there was an inverse relationship
between cognitive impairment and the
intake of vegetables and fruits,
coffee, and tea.
Similar effect modification was seen
between race and
coffee intake (≥ 1 compared with < 1 cup / d) on total and free E2, LH, and FSH concentrations (P = 0.06, P = 0.14, P = 0.01, and P = 0.03, respectively).
This had no effect on the observed relationships
between PD and
coffee or caffeine
intake.
If the aforementioned person's breakfast consists of a cup of
coffee along with a bagel, muffin, or waffle, their protein
intake at breakfast time will likely be
between 2 and 10 grams, resulting in a skewed protein
intake distribution rather than one that is even.
Since the WCRF report, Luo et al [59] studied the association
between the drinking
coffee and the risk of pancreatic cancer in a large population - based cohort study in Japan and concluded there was no increased risk of pancreatic cancer with
coffee intake.
The association
between total
coffee consumption and risk of type 2 diabetes remained similar: the RR for a one - cup increment in consumption was 0.86 (95 % CI 0.82 — 0.89) after multivariate adjustment and 0.84 (0.79 — 0.91) after further adjustment for caffeine
intake.
In a validation study in the original Nurses» Health Study, we found high correlations
between intake of
coffee and other caffeinated beverages assessed with food frequency questionnaire and with four 1 - week diet records (
coffee, r = 0.78; tea, r = 0.93; and caffeinated sodas, r = 0.85)(15).
New research published in the November issue of the journal Hepatology reveals information on the first study to address the association
between liver disease progression related to hepatitis C and
coffee intake.