Not exact matches
To examine the relationship
between dietary intake of major sources of
protein and kidney function, a team led by Woon - Puay Koh, MBBS (Hons), PhD (Duke - NUS Medical School and Saw Swee Hock School of Public Health in National University of Singapore) analyzed data from the Singapore Chinese Health Study, a prospective study of 63,257 Chinese adults in Singapore.
Subjects with renal insufficiency, even subclinical, kidney transplant patients and people with metabolic syndrome or other obesity - related conditions, will be more susceptible to the hypertensive effect of amino acids, especially of the sulphated variety.104 The well - documented correlation
between obesity and reduced nephron quantity on raised blood pressure puts subjects with T2D or metabolic syndrome at risk, even if in diabetics with kidney damage the effects are not always consistent with the hypothesis.12, 105,106 In fact, although some authors have reported a positive influence of a reduction in
protein intake from 1.2 to 0.9 g / kg, over the short term, on albuminuria in T2D, 107 the same authors have subsequently stated instead that
dietary protein restriction is neither necessary nor useful over the long term.108
The method of increasing
dietary pulse
intake while maintaining caloric balance
between the study arms differed across protocols: 15 trials replaced non —
dietary pulse carbohydrates (e.g., bread products, canned spaghetti, oat bran), 5 trials replaced animal
protein, 3 trials emphasized
dietary pulse
intake to achieve a low - glycemic diet, and 3 did not specify the method.
This discrepancy
between short - and long - term effects of
protein intake can be explained by differences in energy content and / or in long - term and acute effects of
dietary protein.
We stratified all analyses by country, mainly because of the large
dietary heterogeneity
between countries, specifically
between northern and southern Europe, e.g., relatively high
protein intake in Spain and low
protein intake in Germany and Sweden.
In this current study, with low heterogeneity
between the eight countries, we observed a positive association for total and animal
protein and type 2 diabetes risk, independent of known type 2 diabetes risk factors and
dietary factors including fat, saturated fat, and fiber
intake.
Further, we were able to adjust our associations for a wide range of potential risk factors for type 2 diabetes and
dietary factors, so the observed positive association
between protein intake and type 2 diabetes is likely to be explained by
proteins per se.