Not exact matches
Multi-colored metastasis in the peritoneal lining of the abdomen comprised of red and yellow fluorescent
cells demonstrating that pancreatic
cancer spreads through interactions
between different groups of
cells.
Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed
between the hepatocellular carcinomas and the liver
cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the
cells was actually similar
between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were
different in patients without such infections.
The notable differences in fluorescence intensity observed
between normal
cells and
cancer cells, as well as
different cancer types, provide important points of differentiation
between different cell types and make these probes promising tools for
cancer detection and diagnostics.
«The
cancer stem
cells actively regrow and respond to the induced damage or apoptosis (
cell death) caused by chemotherapy in
between the
different cycles, similar to how normal tissue stem
cells respond to wound - induced damages.»
The team has already revealed a huge amount of genetic diversity
between cancer cells taken from
different sites within each man's prostate.
Studying
cancer with single -
cell technology will allow us to unlock the interactions
between different types of
cells in tumors — and monitor how these interactions change over time, affecting patients» outcomes.
• Detect Zika virus in blood and urine samples within hours and distinguish
between its African and American strains • Distinguish
between Zika and dengue • Discriminate
different types of bacteria, like E. coli • Detect
cancer cell mutations • Detect antibiotic resistance genes • Read human genetic information from saliva sample
Researchers are also trying to learn about: - The level of MM - 121 that remains in the human body at
different time points when MM - 121 is combined with docetaxel or pemetrexed - The relationship
between the biomarker, heregulin, and
cancer cell growth (disease progression) in people dosed only with docetaxel or pemetrexed.
To directly evaluate the relationship
between ABL family kinases and metastasis, we analyzed ABL1 and ABL2 protein abundance in MDA - MB - 231 — derived breast
cancer cell lines with
different organ metastasis tropisms (19).
Beyond the expansion of the collection of barcoded
cell lines for testing larger panels of compounds, next steps will include determining whether PRISM can be used to study the complex interactions
between different cell types found within tumors, or to study tumor evolution during
cancer development or after
cancer treatment.
It means that
cancers are not the same —
between types of
cancers,
between cancers in
different individuals, even
between cancer cells within the same person.