Sentences with phrase «between efficacy and safety»

There is a balance between efficacy and safety, and while solanezumab was not that powerful, the idea was that the Food and Drug Administration, in approving the first disease - modifying Alzheimer's treatment, needs to have a drug that can be used safely, and first do no harm.»

«A successful vaccine requires a fine balance between efficacy and safety — vaccines made from attenuated live viruses generally offer fast and durable immunity, but sometimes with the trade - off of reduced safety, whereas inactivated and subunit viruses often provide enhanced safety but may require several doses initially and periodic boosters.

The ingredients are aloe Vera and potassium nitrate, which allows our gels to push the boundaries between efficacy and safety.

Not exact matches

1) Facilitate safe off - label use of existing vaccines — Support collaboration between the zoological community and conservationists in the field to determine the safety as well as efficacy of existing distemper vaccines that could be, at a minimum, administered opportunistically to endangered wild carnivores whenever they are being handled (e.g. during radio - collaring exercises or when being translocated to mitigate human - wildlife conflict).

Many factors may cause differences between current expectations and actual results including unexpected safety or efficacy data observed during preclinical or clinical studies, clinical trial site activation or enrollment rates that are lower than expected, changes in expected or existing competition, changes in the regulatory environment, failure of Syndax's collaborators to support or advance collaborations or product candidates and unexpected litigation or other disputes.

Paris, France, April 3, 2018, 5.35 pm CET — GenSight Biologics (Euronext: SIGHT, ISIN: FR0013183985, PEA - PME eligible), a biopharma company focused on discovering and developing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, today announced topline results from the REVERSE Phase III clinical trial evaluating the safety and efficacy of a single intravitreal injection of GS010 (rAAV2 / 2 - ND 4) in 37 subjects whose visual loss due to 11778 - ND4 Leber Hereditary Optic Neuropathy (LHON) commenced between 6 and 12 months prior to study treatment.

We are currently investigating the role of various T - cell costimulatory pathways in regulating the humoral and cellular responses to and between DENV and ZIKV, and are defining the particular pathways that should be targeted to maximize safety and efficacy of vaccines.

It is at present unknown whether an optimal balance between safety and efficacy can be achieved with the combination therapy of GH and IGF - I, since this combination has been evaluated in only a small number of patient populations and in studies of a relatively short duration.

You will learn essential vocabulary, the difference between extracts, tinctures, capsules, infusions, and decoctions, standardized, holistic balance, as well as the safety and efficacy...

An efficacy and safety comparison between different stentriever designs in acute ischaemic stroke: a systematic review and meta - analysis.

Consumers are willing to spend more money on premium green products, but pet parents will compare pricing between multiple eco-friendly items that seem to boast similar ingredients, safety and efficacy, ultimately choosing the most cost - effective option — a trend that Holmes has recognized.

Entropic Ltd. (Kildare, Ireland) 12/2007 — 07/2009 HVAC Engineer & Technical Sales • Served as project manager of HVAC and heat recovery equipment design, sales, and installation for large scale commercial and residential applications • Created specifications for ventilation and heat recovery equipment for multiple clients including AVIVA Stadium DKIT Engineering building and Genzyme Waterford • Utilized expertise and communication skills as liaison between customers and suppliers • Trained and supervised sales, customer service, and technical staff ensuring effective operations • Developed proficiencies in computer programs such as AutoCAD and in - house design programs • Employed LEAN techniques to maximize project efficacy in a safety conscious manner • Oversaw stock control, order entry, and timely delivery of products