The study is the first to establish a close link
between epigenetic modifications on a cancer gene and the risk of developing the disease, says Robert Philibert, a behavioral geneticist at the University of Iowa in Iowa City.
Not exact matches
DNA methylation is one form of
epigenetic modification being studied by scientists trying to understand how the same genetic code can produce so many different cells and tissues as well as differences
between individuals as closely related as twins.
Schrock: I'm sure that's been tried, but one of the new things they found is this specific tie
between the circadian rhythm in our bodies and drug addiction and they found that it is actually through an
epigenetic modification of the circadian rhythm; so our circadian rhythms are reset by these drugs; we actually crave them at certain times of day and that is contributing to the necessity to, you know, relapse and go back on drugs or to get that craving, you know, at a certain point.
The differences
between male and female iPS cells are most pronounced for one of the key processes in the field of
epigenetics: DNA methylation, a
modification that changes the activity of a DNA segment without changing its sequence.
The quality and novelty of the data, leads to new insights into the replication landscape of the human genome and to further unravel the links
between replication, gene expression,
epigenetic modification and 3D genome organization in normal and cancer cells.
Epigenetic modifications, such as DNA methylation or histone
modifications, can be transmitted
between cellular or organismal generations.