Sentences with phrase «between epithelial cells»

Basically, it means that the gaps in between the epithelial cells of the intestine have become wide enough to allow the passage of large macromolecules, undigested foods, toxins and bacteria.

They have tentacle like protrusions that penetrate the tight junctions between the epithelial cells, through to the other side, and use these tentacles to take external surface antigens back in for destruction.

In the small intestine, gluten triggers the release of zonulin, a protein that regulates the tight junctions between epithelial cells and therefore intestinal, but also blood - brain barrier function.

Its only down side (along with the caloric sugar alcohols) is that it may temporarily weaken tight junctions between epithelial cells, effectively creating short term «leaky gut».

Inside the epithelial cell, the tail of E-cadherin binds to a protein called α - catenin, which recruits other proteins that spur assembly and disassembly of actin filaments and is absolutely critical for strong adherence between epithelial cells.

Using colorfully labeled antibodies to light up the new protein under their microscopes, they found that it was present where Listeria entered cells and also present at adherens junctions between epithelial cells.

Not exact matches

Milk sodium concentration is a marker of tight junction closure between mammary epithelial cells; with the onset of secretory activation (stage II lactogenesis) milk sodium concentrations decrease sharply as potassium concentrations increase [14].

Colostrum is characteristically high in sodium (> 30 mmol / L) and low in potassium (< 15 mmol / L) as a result of open paracellular pathways between mammary epithelial cells [14].

«Chronic inflammation of the intestine is thought to be caused by abnormal interactions between gut microbes, intestinal epithelial cells and the immune system, but so far it has been impossible to determine how each of these factors contribute to the development of intestinal bowel disease,» said Hyun Jung Kim, Ph.D., former Wyss Technology Development Fellow and first author on the study, speaking about the limitations of conventional in vitro and animal models of bacterial overgrowth and inflammation of the intestines.

Further tests suggested that epithelial cell progenitors helped by restoring the connection between cells called myoepithelial contractile cells and the lacrimal gland's secretory cells, which produce tears.

According to Dr. Bleich and his co-investigators, «Epithelial barrier function is predominantly dependent on tight junction proteins, which regulate transport into and between cells.

Corresponding to the primary function of epithelial tissues, i. e. forming a barrier between compartments, epithelial cells form tight adhesions between each other, and display only lateral mobility, confined by the basement membrane.

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits.

It has been observed for nearly 80 years that Bps can change colony morphology, and recent studies have shown an association between morphotypes and specificity for body compartments, ability to adhere and penetrate epithelial cells or macrophages, and expression of virulence factors.

Limbal epithelial stem cells (LESCs) reside in the basal layer of the limbal area, at the vascularised junction between the corneal and conjunctival epithelium.

Saliva is often collected for genotyping studies but is rarely used to examine DNA methylation because the proportion of epithelial cells and leukocytes varies extensively between individuals.

Oncologists have suspected for several decades that metastasis usually requires a transition between sticky epithelial cells, which make up the bulk of solid tumors, and thinner, more mobile mesenchymal cells that are often found circulating solo in cancer patients» bloodstreams.

Interestingly, RIPK2 has been demonstrated to be involved in the active growth of CD90 (+) intestinal stromal cells to suggest an «inflammatory» cross-talk between intestinal stromal cells and the epithelial cells (Owens et al., 2013), and we can observe robust activation of RIPK2 in IBD colon tissue sections immunostained with our proprietary pY474 RIPK2 antibody (Salla et al., unpublished observations).

This layer creates a thick physical buffer between the intestinal lumen and the inner epithelial cells.

Barriers called tight junctions guard the pathways between intestinal epithelial cells.

Diversity of tight junctions (TJs) between gastrointestinal epithelial cells and their function in maintaining the mucosal barrier.

The lining of the gastrointestinal (GI) tract is composed of small epithelial cells that act as a barrier between the interior and the exterior of the body.

According to the team, quercetin interferes with a process known as EMT, or epithelial - mesenchymal transition, which loosens the junctions between cells and makes it easier for cancer to get a foothold.

Despite strong support for the proliferative and growth - promoting effects of estrogens on mammary epithelial cells from animal and experimental studies (78, 79), previous studies on the associations between estrogens and breast density showed largely null or inconsistent results.