Sentences with phrase «between gene activity»

Using an array of techniques, including RNA sequencing and targeted gene expression profiling, the researchers searched for links between gene activity and protein production in these tumors and the clinical outcomes of patients.

«When we compared the gene signature activity of glioblastoma cells from around 60 patients we found that a large number of patients could be divided into subgroups that showed a correlation between gene activity, tumor cell characteristics and cell of origin similar to the one we had seen in the mouse study.

Not exact matches

«Gene variant activity is surprisingly variable between tissues.»

Their brains differed in the activity of over a hundred genes that provide cells with energy, influence chemical communications in the brain and strengthen the connection between nerve cells.

Chemical modifications to DNA that change the activity of genes without changing the genes» information differ between homosexual and heterosexual men, researchers from UCLA David Geffen School of Medicine have discovered.

Professor Dale said the correlation demonstrated between the RGA2 gene activity and TR4 resistance opened up new research.

And the mutation that bestows such remarkable longevity is a gene that happens to regulate activity in the insulin / IGF signaling pathway, says Robert Schmookler - Reis of the University of Arkansas, a molecular geneticist who discovered the relationship between the mutation and the superworm's extraordinary life.

In many cases, the activity of particular genes was tied to a single genetic variant, with strong differences in frequency between European and African populations.

The team also recently obtained a grant from the National Medical Research Council in Singapore to pursue a study using the probe to examine the relationship between key Parkinson's disease - linked genes and MAO - B expression and activity to further understand the causes of the disease and illuminate the role of MAO - B in this.

In all, activity levels of dozens of genes in the brain were distinct between the two types of mice, they report.

In their recent paper, the researchers not only looked at the genetic code, but also studied how gene activity varied between the two populations.

This will offer us unique insights into the relationships between epigenetics and gene activity and will help us to better understand the processes that convert a single cell into the many different cell types in the body.»

For example, investigators found that for the mouse immune system, metabolic processes and stress response, the activity of some genes varied between mice and humans, which echoes earlier research.

They found a link between MYC overexpression and the activity of spliceosome - related genes.

Hochedlinger and colleagues pinpointed 49 genes whose activity consistently differed between iPS and ES cells.

When the researchers measured gene activity, they found that the iPS cells were more similar to the ES cells they descended from than to each other, suggesting that the source of the cells explains many of the disparities researchers had noted between the two stem cell types.

The researchers showed these relationships between ecRNA production and gene activity in neurons included genes whose expression is altered by neuronal activity and genes implicated in developmental and neurodegenerative disorders.

Whereas liver and blood gene activity patterns showed the expected differences among the three groupswith human transcription looking similar to that of the chimp, and different from that of the more evolutionarily distant macaquegene activity in the brain revealed stark differences between humans and chimps.

They found hundreds of differences in gene activity between males and females.

The activity of thousands of sperm genes appears to differ between healthy and obese men, suggesting that a man's weight may be passed on to the next generation

The new technique, called Calcium and Light - Induced Gene Handling Toolkit or «Cal - Light,» allows researchers to observe and manipulate the neural activities underlying behavior with never - before - seen specificity, hopefully allowing researchers to identify causality between neuronal activity and behavior.

The researchers discovered that DNA methylation — a fundamental, life - long process in which a methyl group is added or removed from the cytosine molecule in DNA to promote or suppress gene activity and expression — does in fact vary between FLS from the knees and hips of RA patients.

About 16 % of the honeybee's 7500 genes showed a significant difference in activity between the two groups of bees.

The research team behind the study, which is being published in the journal Epigenetics, also found strong links between these altered epigenetic patterns and the activity in genes controlling improved metabolism and inflammation.

The study *, published in the British Journal of Cancer ** today (Wednesday), showed a potential link between the activity of a gene called BCAR4 and the likelihood that a breast cancer tumour will not respond to tamoxifen — widely used to treat women with breast cancer.

Researchers have shown they can distinguish between viral and bacterial infections in children with fever by profiling the activity of genes in a blood sample.

Again, this might be either due to the difference between complete knock out of the genes versus reduction of gbp1, gbp2 expression via RNAi, or due to the activity of GBP1 and GBP2 in other organs.

This difference in the effect on ilp2 mRNA expression could result from the difference between completely removing the activity of these genes in the gbp1, gbp2 ex67 mutant larvae versus partial reduction of their mRNAs in the GBP1, GBP2 double knock downs.

Group research aims to study the relations between nutraceuticals, physical activity, intracellular mechanisms, gene expression and microbiota using a translational approach to characterize the impact in the whole body of metabolic interactions studied in individual organs and tissues (in vitro / ex vivo: skeletal muscle, heart, bone, liver and kidney).

Single - cell experiments show that gene expression is random and «bursty,» Lin said, a feature that can emerge from slow switching between promoter states with different activities.

By combining neuronal tracing with behavioral experiments leading to sensory - driven gene expression of the neuronal activity marker ZENK during magnetic compass orientation, we demonstrate a functional neuronal connection between the retinal neurons and Cluster N via the visual thalamus.

In her essay, she described how the interactions between genes and the environment affect human health and disease, concluding that these environmental influences on gene activity allow people to protect their own well - being by cultivating healthy habits.

There's a positive association between physical activity and genes that affect your circadian clock.