Sentences with phrase «between human patients»

Our finding of similarity in clinical progression between human patients and Huntington's disease monkeys suggests monkeys could become a preclinical, large animal model for the development of new treatments.»

«Our studies took us back and forth between human patients and our mouse model,» said Millar.

Not exact matches

Peris saw the therapeutic relationships as an authentic encounter between two human beings, not a variation on the doctor - patient relationship.

«Thus, also in our century, the Lord, the Holy Spirit, has given us new initiatives with new aspects of Christian life: On being lived by human persons with th ``... If the movements are really gifts of the Holy Spirit, they integrate and serve the Church, and in the patient dialogue between pastors and movements a fruitful form is born, in which these elements become edifying elements for the Church of today and tomorrow

Science Translational Medicine publishes research that matters for human health, filling the knowledge gaps between research and medical application to improve patient care worldwide.

A total of 145 patients has been diagnosed in recent weeks with a strain of the H3N2 animal influenza virus, but it likely has not yet evolved the ability to transmit efficiently between humans

This take on Michelangelo's famous Sistine Chapel image symbolizes the link between human pain patients and the mouse model: The lab - designed SPR inhibitor (in green), shown within the active pocket of SPR itself (in gray with its atomic structure in colored lines), is the «bridge» between the two species.

«The new model enables studies of the complex interactions between host cells, mucus production, and gut microbes in a system that closely mimics the situation in human patients,» Dawson said.

In a second group of experiments using human tissue from patients with pancreatic ductal adenocarcinoma, which accounts for more than 90 percent of pancreatic cancers, Zheng and his colleagues also tracked down a link between the abundance of Sema3D in those tissues and the progression of metastatic pancreatic cancer.

The new study — published October 18, 2016 in the journal Molecular Psychiatry — combined genetic analysis of more than 9,000 human psychiatric patients with brain imaging, electrophysiology, and pharmacological experiments in mutant mice to suggest that mutations in the gene DIXDC1 may act as a general risk factor for psychiatric disease by interfering with the way the brain regulates connections between neurons.

The potential prospects include superintelligent machines, nonaging bodies, direct connections between human brains or between brain and computer, fully realistic virtual reality, and the reanimation of patients in cryonic suspension.

Researchers from Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumor type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.

Of note, 145 of all the oropharyngeal cancer patients were also tested for human papillomavirus (HPV), allowing researchers to compare possible associations between the two viruses.

That's because they may have finally developed a tissue model for the human heart that can bridge the gap between animal models and human patients.

Researchers from Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumour type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.

Of the 22 patients whose tumors successfully grafted, six died before data from the mice were available, but in 13 of the remaining 16 cases, there was a positive correlation between mouse and human results.2 In a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutations.3

In collaboration with Dr. Josh Thaden and Vance Fowler, Duke University Medical Center, we are exploring relationships between bacterial genetic variation, emergence of AMR, and patient outcome in Enterobacter and Escherichia coli Bloodstream Infections (BSI) by leveraging the Duke University Bloodstream Infection Biorepository (BSIB), which contains robust clinical data, bacterial bloodstream isolates, and corresponding human sera and DNA from over 2000 patients with BSI caused by Gram - negative bacteria at Duke Hospital since 2002.

Whereas the derivation of stem cell lines from human embryos is subject to specific regulation by the Human Fertilisation and Embryology Authority (HFEA), UK law does not distinguish between fetal tissue and other tissue from living patihuman embryos is subject to specific regulation by the Human Fertilisation and Embryology Authority (HFEA), UK law does not distinguish between fetal tissue and other tissue from living patiHuman Fertilisation and Embryology Authority (HFEA), UK law does not distinguish between fetal tissue and other tissue from living patients.

These data suggest either that there are limited differences in methylation between patients with diabetes and nondiabetic subjects or that DNA methylation in human adipose tissue is highly heritable.

To build upon the encouraging early discoveries, Helmsley renewed and expanded its Crohn's funding for the Institute in 2013 to begin new work with three major aims: 1) continue studies of individual genes to determine how genetic differences between Crohn's patients and healthy individuals contribute to the disease; 2) evaluate promising small molecules in disease - relevant studies and prioritize insights from genetics to help develop novel therapeutics; and 3) begin basic experimentation in animal models with Crohn's disease to provide the data necessary to begin testing new therapies in humans.

Researchers from SciLifeLab / Uppsala University, Sweden, and the Broad Institute, USA, have identified both similarities and differences between a single tumour type in multiple dogs breeds; a finding they believe parallels the situation in the cancer of human patients.

Her laboratory focuses on (1) the use of next generation sequencing to define the microbiome and host immunologic features in patients with human diseases and (2) developing custom computational tools for the identification of novel human commensals and pathogens in these inpatient populations, and (3) using statistical and functional biological methods to understand the complex interplay between the human microbiome and host biology.

I think we all agree that we over treat prostate cancer in this country compared to what you see in Europe with similar outcomes and so but I think this is where the human or the Cancer Genome Project or at least better biomarkers for looking at mutations that we already know occur in these diseases I think hopefully within the next few years every single patient who is diagnosed with prostate cancer those biopsies will be characterized and then the patients followed, hopefully watchful waiting and we'll ultimately get a correlation between what mutational events predict a rather dormant disease as opposed to a very aggressive disease.

She joined the Pillai lab as a post-doctoral research fellow in 2016 and continues to enjoy her work both treating patients with primary immunodeficiency in the clinic and studying the bridging gap between human primary immunodeficiency disorders and the development of autoimmune disease pathology in the lab.

Conclusions: In an analysis of peripheral blood mononuclear cells and intestinal tissues from patients with inflammatory bowel diseases vs controls, we found that reactivity to intestinal bacteria is a normal property of the human CD4 + T - cell repertoire, and does not necessarily indicate disrupted interactions between immune cells and the commensal microbiota.

These results, also presented at the 2015 European Cancer Congress (ECC2015, abstract # 5BA) today, which involve the group of 1,626 patients with a Recurrence Score between 0 and 10, demonstrated that 99.3 percent of node - negative, estrogen receptor (ER)- positive, human epidermal growth factor receptor 2 (HER2)- negative patients who met accepted guidelines for recommending chemotherapy in addition to hormonal therapy, had no distant recurrence at five years after treatment with hormonal therapy alone.

In rodents, ketogenic diets reduce reactive oxygen species in the brain34 and reduce central inflammation and reactive oxygen species in a model of multiple sclerosis.35 Two clinical papers have found that ketogenic diet feeding of 12 weeks to 6 months reduced signs of liver inflammation in obese patients with nonalcoholic fatty liver disease (in addition to improving various other physiological and biochemical variables).36, 37 Unfortunately, basic research into non-alcoholic fatty liver disease has been hampered by species differences between mice and humans in their hepatic reaction to ketogenic diets.38

We recognize the importance of the relationships between humans and animals and we see our clients and patients as extended family.

The human animal bond between patient and dog is so strong you truly say that.

The human animal bond between patient and dog is so strong, I feel good saying there is a miracle happening there.

Our veterinarians, Dr. Elizabeth Stone, Dr. Liz Noppinger, and Dr. Jennifer Jarvis provide quality, loving care to their patients to improve animals» lives and the precious bonds between animals and humans.

Assessing and alleviating pain in cats is not only a core goal of veterinary medicine, but successfully controlling the pain of a surgical procedure can also strengthen the human - animal bond and even help reinforce the relationship between veterinarian, client and patient.

Although in humans almost all chiari malformation patients has some degree of cerebellar herniation, in dogs cerebellar herniation is not that common and this is the main difference between these 2 species.

Exhibiting compassion and understanding of the bond between a human and his pet, Dr. Funk views his patients as friends and family members that deserve the absolute best.

These results concur with studies on human patients, which report a decrease in insulin sensitivity of between 44 and 72 % in obese subjects compared with normal - weight control subjects (34 — 37).

Another important difference between human and veterinary dental practice is that we tell the dentist when there is discomfort; to ensure that nothing is missed in dogs or cats, our patients require a thorough oral examination as part of a dental scaling procedure.

The bond between our patients and their humans can run the gamut from pathological attachment to disposable companions, and anywhere in between.

The goal is to strengthen the human - animal bond between our patients and their families while giving patients the best care possible to live a long and healthy life.

Zeng lived next to the hospital and would recall in his early paintings, scenes of doctors and fearful patients in emergency rooms, and the proximity between humans and flesh to underscore human frailty.

In biomedicine, just to give you an example of what PCAST can do, we can harness the historic convergence between life sciences and physical sciences that's underway today; undertaking public projects — in the spirit of the Human Genome Project — to create data and capabilities that fuel discoveries in tens of thousands of laboratories; and identifying and overcoming scientific and bureaucratic barriers to rapidly translating scientific breakthroughs into diagnostics and therapeutics that serve patients.

The issue of charging foreign patients is one of checks and balances, and is underpinned by a clash between the human, moral considerations and the economic facts at play.

Act as a bridge between the patient and Su Clinica's services as well as other community health, human, and social service organizations.

Due to the population this office services, I also function as a liaison between patients and insurance companies or other human resource organizations.