Moir and Tanzi decided to explore the connection
between innate immunity and Alzheimer's disease.
Not exact matches
The gene expression similarities
between this common condition and the current findings in late - stage RP suggest that the canine RP models could serve as stand - ins to evaluate the effectiveness of pharmaceutical interventions that target
innate immunity pathways in AMD
By 2008, when Moir stumbled on the parallels
between amyloid - beta and LL - 37, Tanzi had discovered additional genes associated with Alzheimer's that were also related to
innate immunity, the part of the human immune system that is shared with worms, flies, spiders and other primitive creatures.
By showing that ligands associated with
innate immunity enable dendritic cells to initiate T cell responses, this work provided the key missing link
between the
innate and adaptive immune responses.