Kravitz has a background in studying Parkinson's disease, and when he began conducting obesity research a few years ago, he was struck by similarities in behavior
between obese mice and Parkinsonian mice.
Not exact matches
Probing the link
between adiponectin deficiency and metabolic disorders like diabetes and obesity, researchers from the Albert Einstein College of Medicine in New York City injected adiponectin into wild - type
mice, diabetic
mice, and
obese diabetic
mice.
«Understanding how the drug also enables crosstalk
between fat cells and the liver in
obese mice allows us to see more of the amlexanox picture — and also sheds light on communication
between different tissues in the body.»
In 2005, together with Washington University microbiologist Jeffrey Gordon and others, Knight used the tools to catalog the microbes that inhabit the intestines of lean and
obese mice, in hopes of uncovering relationships
between microbes and metabolic health.
In rodents, ketogenic diets reduce reactive oxygen species in the brain34 and reduce central inflammation and reactive oxygen species in a model of multiple sclerosis.35 Two clinical papers have found that ketogenic diet feeding of 12 weeks to 6 months reduced signs of liver inflammation in
obese patients with nonalcoholic fatty liver disease (in addition to improving various other physiological and biochemical variables).36, 37 Unfortunately, basic research into non-alcoholic fatty liver disease has been hampered by species differences
between mice and humans in their hepatic reaction to ketogenic diets.38