Mental illness has reached crisis proportions, yet we still have no clear links
between psychiatric diagnoses and what's going on in the brain — and no effective new classes of drugs.
Not exact matches
There already exists a bidirectional relationship
between all of the major chronic diseases and
psychiatric diagnoses (patients who struggle with chronic diseases are more likely to be depressed and vice versa).
Digby is interested in the
psychiatric diagnosis and the relationship
between the brain and environment.
In the future, the ability to understand and contextualize the report of early adverse or traumatic experiences will fundamentally influence the approach to
diagnosis and treatment of all
psychiatric entities.1 This proposition is reminiscent to some extent of the longstanding distinction
between the categorical and dimensional approaches to conceptualization.
A review of twenty studies on the adult lives of antisocial adolescent girls found higher mortality rates, a variety of
psychiatric problems, dysfunctional and violent relationships, poor educational achievement, and less stable work histories than among non-delinquent girls.23 Chronic problem behavior during childhood has been linked with alcohol and drug abuse in adulthood, as well as with other mental health problems and disorders, such as emotional disturbance and depression.24 David Hawkins, Richard Catalano, and Janet Miller have shown a similar link
between conduct disorder among girls and adult substance abuse.25 Terrie Moffitt and several colleagues found that girls diagnosed with conduct disorder were more likely as adults to suffer from a wide variety of problems than girls without such a
diagnosis.26 Among the problems were poorer physical health and more symptoms of mental illness, reliance on social assistance, and victimization by, as well as violence toward, partners.
The clinical
diagnosis of hypochondriasis was made with the Structured Diagnostic Interview for Hypochondriasis based on operationalized DSM - III - R criteria.27 Interrater agreement with this instrument is 96 %, and the univariate correlation
between the interview responses and self - report questionnaire scores is 0.75.27 The DSM
diagnosis of hypochondriasis specifically excludes hypochondriacal symptoms that are better explained by another, comorbid
psychiatric disorder or by major medical illness.
Across the 8 years of the study, a significant negative correlation
between family income and child
psychiatric diagnoses (r = − 0.13, P <.001) and number of symptoms (r = − 0.15, P <.001) was observed.
Furthermore, a large proportion of comparison participants qualified for a lifetime
psychiatric diagnosis (combining subthreshold and full
diagnoses)(Table 4), sometimes exceeding population rates.40 It seems more compelling that differences at the mean age of 41 years
between probands and comparison participants reflect differential development, especially because findings are highly consistent with other, briefer follow - up studies.
Similarly, another recent functional imaging study focused on 1129 community youths (mean age 15.5 years) and investigated the relationship
between psychopathology and activation of the executive system during a working memory task.9 Overall psychopathology was associated with hypoactivation in the frontal pole, anterior cingulate, anterior insula and precuneus, implicating a network of executive regions across a range of
psychiatric diagnoses.
The
psychiatric diagnosis Reactive attachment disorder (RAD)(DSM - IV - R 313.89) can be understood as the result of significant impairment in the intersubjective sharing of experience
between caregiver and child.
Of more concern were
psychiatric diagnoses of alcohol / drug dependence: among women and men, respectively, lifetime rates ranged
between 19 % — 24 % and 23 % — 40 % among NESSY - Os at age 26; and 11 % — 16 % and 19 % — 27 % among NESSY - Ys at 22.
Children were aged
between 11 and 18 years and met criteria for at least one
psychiatric diagnosis.
Conclusions: These results extend to a paediatrically referred population with previously reported findings in
psychiatric samples documenting good convergence
between structured interview
diagnoses and syndrome congruent CBCL scales.
The DAWBA is a valid hybrid
between a structured and a semi-structured interview for the
diagnosis of child and adolescent
psychiatric disorders according to both the ICD - 10 and DSM - IV [60, 61].
These results extend to a paediatrically referred population previously reported findings in
psychiatric samples documenting good convergence
between structured interview
diagnoses and syndrome congruent CBCL scales.
Conclusions: There are different genetic and family environmental pathways
between infant temperament and
psychiatric diagnoses in this sample of Puerto Rican preschool age children.