Negative correlations have been reported between
bilateral amygdala volume and life history of aggression (Matthies et al., 2012) and between trait anger and local gray matter volume in the left amygdala (Reuter et al., 2009) in healthy subjects.
Compared to controls, patients with schizophrenia demonstrated smaller
bilateral hippocampus,
amygdala, thalamus and accumbens
volumes as well as intracranial
volume, but larger
bilateral caudate, putamen, pallidum and lateral ventricle
volumes.
Specifically, males on average had larger
volumes and higher tissue densities in the left
amygdala, hippocampus, insular cortex, putamen; higher densities in the right VI lobe of the cerebellum and in the left claustrum; and larger
volumes in the
bilateral anterior parahippocampal gyri, posterior cingulate gyri, precuneus, temporal poles, and cerebellum, areas in the left posterior and anterior cingulate gyri, and in the right
amygdala, hippocampus, and putamen.