Not exact matches
Once CAT - tailed proteins are imported into the mitochondria, they form
aggregates that may act
as a seed, and ultimately
bind proteins free of defects that have vital roles for the cell» explains Toshiaki Izawa, first author of the study, together with Sae - Hun Park.
But unexpectedly in this case, «we didn't see improvement in soil
aggregate stability even though soil organic carbon concentration increased,» Blanco says, noting that soil particles usually
bind together more strongly in
aggregates as soil organic carbon concentrations rise.
In further testing, BIIB054 selectively
bound aggregated AS in tissue samples from people with PD and with Dementia with Lewy Bodies (DLB — a related disease of
AS - driven neurological aging), while leaving native
AS alone.
Those inducedAbs would epitope map to recognize the C - terminus of
AS as well as full - length and N - terminal truncated AS species, and also bind to oligomeric AS aggregate
AS as well as full - length and N - terminal truncated AS species, and also bind to oligomeric AS aggregate
as well
as full - length and N - terminal truncated AS species, and also bind to oligomeric AS aggregate
as full - length and N - terminal truncated
AS species, and also bind to oligomeric AS aggregate
AS species, and also
bind to oligomeric
AS aggregate
AS aggregates.
(6) So it's entirely possible that the available PRX002 present in the CSF is entirely occupied with
binding brain
AS aggregates, leaving few molecules of the antibody free to capture the residual monomeric
AS.