The second gene, TNFRSF6B, encodes a receptor related to those that
bind tumor necrosis factor (TNF)-- a key chemical signal for triggering inflammation in IBD as well as in patients with other autoimmune disorders such as rheumatoid arthritis and psoriasis.
Not exact matches
Han et al. demonstrated that in Caco2 cells, extracellular NAD + inhibited the
binding of NF - kB to DNA by blocking the transcription of different genes involved in both inflammatory and aging pathways (interlukin - 6, interlukin - 1 beta,
tumor necrosis factor alpha) 27.
TIA - 1 and TIAR are related proteins that
bind to an AU - rich element (ARE) in the 3» untranslated region of
tumor necrosis factor alpha (TNF - alpha) transcripts.
Interferons Inhibit
Tumor Necrosis Factor --LCB- alpha -RCB-- mediated Matrix Metalloproteinase - 9 Activation via Interferon Regulatory Factor - 1
Binding Competition with NF --LCB- kappa -RCB- B