Plank and her team attached their estrogen -
binding aptamers to the other important part of their device: the carbon nanotube thin film field effect transistor (CNT FET).
The team tested two different estrogen -
binding aptamers: one that was 35 units long and another that was 75 units long.
The estrogen -
binding aptamers that Plank and her colleagues used were first developed by Ken McNatty, a professor of reproductive biology at the Victoria University of Wellington.
Not exact matches
But if a sample is exposed to such an
aptamer library, a complex molecule is going to
bind with a lot more sequences than a simple one.
But the
aptamers were designed to
bind either to an anticancer drug called doxorubicin or an antibiotic called kanamycin.
Some
aptamers can
bind to a specific virus, and others can grab certain kinds of cells or attach themselves to vitamins.
They grafted «
aptamers» — synthetic DNA molecules that
bind to specific target biomarkers — to DNA backbones.
When added to human serum, the
aptamers bind to biomarkers before being analysed by passing through a nanopore detector.
If a sample contains gluten, the substance can
bind to one of three capture agents, which can be antibodies or a DNA - based
aptamer, that specifically latch onto gluten proteins from certain sources.
SELEX uses natural selection to find the small strands of DNA called
aptamers (the other dancers) that
bind specifically to the target.
One end of the homing beacon is made up of a DNA
aptamer, a small piece of DNA that can be selected from a pool of billions of candidates based on its ability to
bind tightly to a particular target.
Our group seeks to investigate the use of chemically - modified nucleic acid
aptamers, single stranded DNA or RNA sequences that specifically
bind to a diverse variety of targets, in biosensing and catalysis.
Dr. Maria DeRosa's research examines a type of nucleic acid called «
aptamers» that can fold into 3D nanoscale shapes capable of
binding tightly to a specific molecular target.