Sentences with phrase «binding avidity»

One unifying aspect of these methods is that we are expecting extracellular interactions to be very weak, and so we purposefully increase binding avidity when performing our receptor interaction screens experiments by oligomerising the protein probes.

Not exact matches

By examining a number of receptor systems (see figure), the researchers demonstrated that receptor system response can be characterized as being either avidity - controlled, which depends primarily on ligand capture efficiency; consumption - controlled, where the ability to internalize surface - bound ligand is the primary control parameter; and dual - sensitive, in which both the avidity and consumption parameters are important.

T Cell Receptor Signaling Can Directly Enhance the Avidity of CD28 Ligand Binding.