Sentences with phrase «binding in»

He pioneered the labeling of receptors by reversible ligand binding in the identification of opiate receptors and extended this technique to all the major neurotransmitter receptors in the brain.

These targets were identified based on the presence of predicted regulator binding sites or experimental regulator binding in the target promoter, and / or changes in the target gene's transcript levels in regulator mutant strains.

The rationale behind the project is that acetylcholine plays are role in cognitive functioning and that there is a subgroup of schizophrenia patients that have reduced density and M1 receptor binding in the hippocampus and dorsolateral prefrontal cortex that are referred to as «muscarinic receptor - deficit schizophrenia» or MRDS.

Of 17 regulatory variants identified in the two genes with regulatory variant burden, we show that at least six alter transcription factor - DNA binding in human neuroblastoma cells.

The authors unveil an oppositional implementation of enzyme substrate binding in each aaRS Class.

«We're looking for molecules that restore DNA binding in MODY1 patients.

By entering the Contest, entrants fully and unconditionally agree to be bound by these rules and the decisions of the judges, which will be final and binding in all matters relating to the Contest.

«A lot of work then went into confirming this binding in the lab and not least to show that parasites from non-immune children with severe malaria symptoms in Tanzania often bound EPCR,» she continues.

«Together with The National Institute for Medical Research Tanzania, we are in the process of preparing phase I trials for a vaccine to prevent parasite binding in the placenta and malaria during pregnancy,» he explains.

Electrodes were placed into their subcallosal cingulate, an area located in the centre of the brain that has been shown to have altered serotonin binding in patients with anorexia.

The group is currently investigating how dismantling this extracellular turret will improve drug access and binding in T - type channels.

The study, «Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF - TNF - RII binding in rheumatoid arthritis,» which will be published online June 6 in The Journal of Experimental Medicine, may help explain the divergent efficacies of different TNF - targeting drugs.

The ruling is not technically binding in other counties with pending tobacco cases, but Bill Ogle, a lawyer working on Proctor's behalf, hoped the Duval ruling would have persuasive sway in other counties and help develop a consensus for Proctor's side.

The limitation of ChIP - seq is that it can not deliver a conclusive picture of transcription factor binding in a single cell because it samples events in a population after the cells have been exposed to various toxic chemicals.

«What is new is the rational design of the binding site of the MIP to maximise specific binding in the very complex aqueous medium [containing a mixture of sweat and deodorant formulation] in which the MIP needs to function,» says Haupt.

By participating in the Contest, each entrant unconditionally accepts and agrees to comply with and abide by these Official Rules and the decisions of the American Association for the Advancement of Science («AAAS» or «Sponsor») which shall be final and binding in all respects.

The third was entered into verbally when Theresa May chose to up the rhetoric at the 2016 Conservative conference, and is not binding in any way.

Yes In order to be binding in the United States (US), a treaty must be ratified by two thirds of the Senate (67 Senators).

In order to be binding in the United States (US), a treaty must be ratified by two thirds of the Senate (67 Senators).

The ruling will prove to be a very big boost to the Brexiteers as confused, bewildered Remain MPs vote for Article 50, binding them in for the journey towards the cliff's edge.

However, when it comes to ratification of a negotiated treaty and implementing it as legally binding in the United States, that is left to the legislative branch, and specifically the Senate (the House of Representatives does not vote on treaties).

It will be legally binding in a way that the ruling of the highest court in the law is not.

Postmortem studies of Northern Plains American Indian infants revealed that prenatal cigarette smoking was significantly associated with decreased serotonin receptor binding in the brainstem.

The random drawing will be conducted on or about July 6th, 2009 by Sponsor whose decisions on all matters relating to this Sweepstakes are final and binding in all respects pertaining to this Sweepstakes.

on the process take a look at this blog post on postpartum belly binding in Denton County, TX.

Fold your remaining bias binding in half to find the center, and pin this, centered, to the neck edge.

By submitting an Entry, each Participant (whether declared a Winner or not) agrees (and agrees to affirm such in writing) to (i) abide by and be bound by these Official Rules and the decisions of DeliciousBaby on all matters relating to this Giveaway which decisions are final and binding in all respects, (ii) waive any right to claim ambiguity in the Giveaway or these Official Rules, (iii) forever and irrevocably release, discharge, indemnify and hold harmless the Giveaway Entities, and each of their respective officers, directors, licensors, employees, representatives and agents (collectively, the «Released Parties») from any liability, claims, demands, and cause of action from personal injury, loss or damage, including death, or property damage, theft, or loss suffered or resulting in whole or in part, directly or indirectly, from participation in this Giveaway or the use, misuse or acceptance or possession of the Prize or any portion thereof, or participation in any Giveaway - related activity; (iv) grant DeliciousBaby (where permitted by law) the right to use their name on a worldwide basis, in all forms of media, in perpetuity without review or further compensation and, (v) warrant and represent that the use of the materials submitted in this Giveaway will not violate the rights of any third parties.

Publication of Proof that Cot Death Babies Show Physiological Effects of Gaseous Poisoning: «Decreased Kainate Receptor Binding in the Arcuate Nucleus of the Sudden Infant Death Syndrome», Journal of Neuropathology and Experimental Neurology 1997; 56:1253 - 61: proof that cot death babies have neurochemical deficits consistent with poisoning by nerve gases.

Read more about the benefits of belly binding in this beautiful blog.

Polterock says, «I feel more free on the water than being binding in to like a wakeboard you know».

While a release clause is not legally binding in the sense that it forces Liverpool to sell to us, it IS legally binding as a clause of a worker's contract.

The deals will be binding in the game though, so don't worry about getting DeAndre Jordan - ed.

While the O'Bannon precedent is influential in most of the country, it is fully binding in federal districts governed by the Ninth Circuit (which includes federal district courts in Alaska, Arizona, California, Hawaii, Idaho, Montana, Nevada, Oregon and Washington).

But, the binding in my Super Natural Cooking is also coming out.

Eggs and egg yolks provide texture and binding in many recipes and are used primarily as emulsifiers, rather than for flavoring foods.

I omit breadcrumbs; a common ingredient used for binding in these recipes.

This ensures good texture and good binding in a more consistent manner.

It is less in carbs and gives a nice binding in recipes.

In terms of sweetener, that might be okay, but agave also provides some of the moisture and binding in this recipe, so you want to be careful substituting a dry for a wet or your bread might come out dry or crumbly.

Not that you probably need much binding in pancakes (the eggs probably would have been enough) but since I was using gluten free flours, I wanted to make sure the pancakes didn't crumble apart.

Hm — the problem with finding a substitute is that sweet rice flour acts as the binding in gluten - free baking.

Martin himself was overawed at the thought of the tradition to which he was binding himself in a friary lately reformed under its own volition.

The publisher adds to the hype by binding in a ribbon, suggesting that this is not simply another translation but a sacred work in its own right.

I do not forget the position assumed by some that constitutional questions are to be decided by the Supreme Court, nor do I deny that such decisions must be binding in any case upon the parties to a suit as to the object of that suit, while they are also entitled to very high respect and consideration in all parallel cases by other departments of the government.

Since there are many ways, in the view of non-dualist Hindus, to know God and to love and serve him, their tendency would be to hold that the Christian revelation, though binding on Christians, was not necessarily binding in every detail on non-Christians.

Guess what, morality is not something that is binding in the sense that it physically prevents you from doing something.

The bible is up to its binding in incest and general fornication.

Furthermore, the American bishops in their pastoral letters on peace and the economy have distinguished between principles and their applications, and stated that the latter are «not binding in conscience.»

The Maudoodi school, on the other hand, accepts only the Qur» an and the Hadith as the infallible sources of law and does not regard the decisions of the medieval jurists as binding in all cases.

Unfortunately for the prosecution, Catholic moral teaching is not legally binding in Victoria, Australia.