Publishing in the journal Proceedings of the National Academy of Sciences the scientists report that the upregulation of the PGC - 1α gene brought about reduced
biological markers of the disease and improved function in the mice.
Not exact matches
Researchers at Stanford University School
of Medicine have identified several new
biological markers to measure the progression
of the inherited neurodegenerative disorder Huntington's
disease (HD).
«This opens a new door in identifying
biological markers for dementia since we might consider using the brain's processing
of speech sounds as a new way to detect the
disease earlier,» says Dr. Claude Alain, the study's senior author and senior scientist at Baycrest's Rotman Research Institute (RRI) and professor at the University
of Toronto's psychology department.
In the study, the children that developed severe disabilities or died from TBM had the highest levels
of these
biological markers, and the levels increased over time, suggesting that this information could be used to help predict
disease outcome.
In this regard, intense research efforts are being channelled into finding new
biological markers that can provide information about the different stages
of the
disease and allow its early detection, and thus facilitate its management.
«We've got a
marker for
biological aging — telomere length — so we're studying whether we can relate it to the increased risk
of getting some
of these age - associated
diseases.
Researchers have identified two new
biological markers of cystic fibrosis (CF), a genetic
disease which affects children and young adults, leaving them with lifelong health complications including digestive problems and persistent lung infections.
«There are few good
biological markers for this
disease and miRNA could help unravel many
of its complexities.»
Non-overweight individuals in their late 60s, 70s, and early 80s who have no outward symptoms
of Alzheimer's are more likely than their heavier peers to have
biological markers (or biomarkers)
of the
disease, the study found.
But the new research looked beyond amyloid and tau levels, for other
biological markers of Alzheimer's
disease in seemingly healthy adults.
The net effect
of this human study was a dramatic reduction in
biological markers associated with cardiovascular
disease.
Telomere length is arguably the best
marker of biological age, and shorter mean telomere length, usually measured in your white blood cells, is associated with increased risk
of heart
disease, obesity, cancer, stroke, dementia, and premature death (2).