The potential
biological mechanisms of obesity effects on depression: A systematic review of the literature and knowledge mining
The two different types of potential effects on early programming of pro-inflammatory responses (Gluckman et al., 2005; Rickard and Lummaa, 2007) suggest the need to examine two indirect pathways in models examining potential
biological mechanisms of influence from parenting to later health outcomes.
Beginning with a brief lecture on
the biological mechanisms of hormone action and synthesis within the brain, Dr. Silbert will explore the concept and role of biology as craft.
Amgen's approach is to understand the fundamental
biological mechanisms of disease in order to determine what type of medicine is most likely to deliver optimal efficacy and safety.
As neuroscientist Larry Cahill explained in a recent article for the Dana Foundation, and as these new findings show, «
the biological mechanisms of brain aging and disease can not be assumed to be the same in men and women.»
An overview on
biological mechanisms of PPARs.
The biological mechanisms of lifespan extension through calorie restriction are not fully understood, but researchers say it may involve alterations in energy metabolism (as mentioned above), reduced oxidative damage, improvements in insulin sensitivity, reduction of glycation, modulation of protein metabolism, downregulation of pro-inflammatory genes and functional changes in both neuroendocrine and autonomic nervous systems.
It brings a scientific approach to traditional medicinal practices, with research on both clinical outcomes and
biological mechanisms of action.
Dr. David Sinclair, Co-Director of
the Biological Mechanisms of Aging at Harvard Medical School was named to the Times Magazine list of «Most Influential People in the World» after his research found a key cause of aging and a potential weapon to reverse it.
Not only is this a novel way to study basic
biological mechanisms of these commonly targeted receptors inside the brain and individual neurons, but it's also a tool scientists can use to study specific effects of drugs in various regions of the brain.
From the 2017 nomination pool, the GFMR selected JAX's Kaczorowski lab as one of only a handful of recipients of a Glenn Award for Research in
Biological Mechanisms of Aging, a one - time $ 60,000 grant awarded «to augment research» in the chosen labs.
Facilitate cross-disciplinary research programs focused on understanding
the biological mechanisms of lymphoid cancers for the development of novel therapeutic treatments for these cancers.
The mouse example illustrates that there are powerful genetic factors influencing
the biological mechanisms of addiction.
Cell
biological mechanisms of activity - dependent synapse to nucleus translocation of CRTC1 in neurons.
Scientists in our group combine methods development, data generation and analysis with hypothesis generation and experimental testing to obtain insights into
biological mechanisms of disease.
Obesity in these mice resembles several important clinical features of human obesity such as weight gain and disturbance of metabolism, and this mouse model was ideal for unraveling any underlying
biological mechanisms of pancreas cancer that are put in motion by obesity.
«When you match physiologic changes in the brain with behavioral impairment, you can start to understand
the biological mechanisms of this disorder, which may help improve diagnosis, and, in time, treatment.»
Howard Hughes Medical Institute, Joslin Diabetes Center and the Paul F. Glenn Laboratories for
the Biological Mechanisms of Aging, Harvard Medical School, Boston, MA 02115, USA.
These findings for the first time provide clear clues towards the underlying
biological mechanisms of intelligence,» says Danielle Posthuma, Principal Investigator of the study.
Imagine you were interested in
biological mechanisms of social interactions.
The authors suggest several
biological mechanisms of breast milk may explain their results, including that breast milk contains many immunologically active components and anti-inflammatory defense mechanisms that influence the development of an infant's immune system.
As Pariante says, «It's about not wasting all this time if an anti-inflammatory can tackle
the biological mechanism of depression.»
«
Biological mechanism of a leading cause of childhood blindness revealed in new research.»
«Based on these findings, I might guess that this type of cancer is less related to sun exposure and more related to
a biological mechanism of alcohol damaging DNA or preventing DNA repair.»
The purpose of this study is to 1) investigate the morphology of the pigment producing cells (melanocytes) and determine if any ultrastructural differences exist among varying appaloosa genotypes, and 2) examine previously associated genes to determine
the biological mechanism of pigment loss.
Not exact matches
Pharmaceutical scientists hope for a moment
of chemical serendipity, despite often not fully understanding the complexity
of the
biological mechanisms they're targeting — or why something might fail in humans when it works so neatly in a mouse model.
And a third, different kind
of gene therapy from Spark Therapeutics — to treat a rare inherited form
of blindness — is likely to be approved by the end
of 2017, too, making this year a landmark for treatments that manipulate the body's own
biological mechanisms in novel new ways to fight deadly diseases.
His idea is essentially «theistic evolution» — belief that God has established evolution as the
mechanism by which He has introduced complexity and diversity into the
biological sphere
of life on earth.
There's still Lenski's E. coli to contend with and a host
of other examples demonstrating purely natural
mechanisms producing
biological novelty.
The figure
of Don Juan is an imaginative impossibility in our time because he comes from a period in which the human being was understood not merely as a
biological machine, generated randomly out
of the incessant flux
of an aleatory universe, but as a radiant and terrible enigma, dangerously and daringly poised between beast and angel, hell and heaven, the elemental abyss and the infinite God: a period in which it was still just possible to believe that human freedom was not merely the all - but - illusory residue
of a random confluence
of mindless physical forces and organic
mechanisms, but a glimpse
of the transcendent within the world
of matter.
This puts the problem
of the boundary conditions, which have to be maintained all the time in both simple and complex examples
of biological mechanisms, as it appeared to one
of the most able physicists
of his time who had given particular thought to these problems.
I have said above that even the simplest
biological mechanism is to a superlative degree more complex than the most complex
of humanly constructed machines.
On materialism the will, along with the sense
of self that actualizes it, is merely a feature
of the human organism and is no less prone to error than the
biological mechanisms responsible for inaccurately manifesting the transgendered person's identity.
This article uses the
mechanism of biological evolution to develop a theory
of depression / anxiety disorders.
In other words, once you have a selective
mechanism which ensures that forms which produce more offspring and tend to last longer become more numerous, then you have the directiveness which is characteristic
of biological and ultimately
of man - made
mechanisms.
On the contrary, it is always meaningful to ask
of a
mechanism, whether a
biological mechanism or a man - made
mechanism, «What is this for?»
Although most scientists working in the area think exadaptation or similar
mechanisms can explain the emergence
of complex
biological forms, most would probably admit that the issue is not fully settled.
In one important way, Intelligent Design's argument is in a much weaker position than traditional cosmological arguments, for empirical results in biology could show that the
mechanisms of neo-Darwinism are sufficient to explain the existence
of complex
biological forms, and in this case the motivation for Intelligent Design's theory would collapse.
The
biological link between the subjective sensation
of effort and the physiological changes occurring during exercise is
of crucial importance, because it provides a
mechanism by which the RPE could, in theory, contribute to the regulation
of exercise performance, the limit to exercise and pacing strategy.
, Advances in experimental medicine and biology; integrating population outcomes,
biological mechanisms and research methods in the study
of human milk and lactation (2002/05/25 ed., pp.207 - 216).
It's all part
of the
biological response
mechanisms that have been ingrained in us to help make this whole breastfeeding thing work.
Post-partum depression poses substantial adverse consequences for mothers and their infants via multiple direct
biological (i.e., medication exposure, maternal genetic factors) and environmental (i.e., life with a depressed mother)
mechanisms.8, 9 From the earliest newborn period, infants are very sensitive to the emotional states
of their mothers and other caregivers.10, 11 Maternal mood and behaviour appear to compromise infant social, emotional and cognitive functioning.11 - 15 As children grow, the impact
of maternal mental illness appears as cognitive compromise, insecure attachment and behavioural difficulties during the preschool and school periods.6,16 - 19
Breastfeeding is the natural
biological conclusion to pregnancy and an important
mechanism in the natural development
of the infant.
What, EXACTLY is the
biological mechanism whereby fear and tension causes any
of the following: Retained placenta Massive PPH Cord prolapse Shoulder dystocia Nuchal cord 4th degree tear Meconium aspiration Chorioamnionitis
Kind
of a
biological protective
mechanism to insure that a women would be physically ready to support another pregnancy.
In the New Beginnings article, Kippley goes well beyond a dry description
of biological mechanisms connected to fertility and hormonal shifts.
We are still far from having conclusive evidence regarding the
biological mechanism (s) that may explain a link between breastfeeding and the prevention
of obesity.
However, evidence
of an underlying
biological mechanism is weakened by the results
of our post hoc analysis, which tended toward lack
of homogeneity between African American and other ethnic groups.
The first stem cells capable
of making placenta could enable researchers to better understand the
biological mechanisms behind many failed early pregnancies
Tsai says her team wants to probe this
biological mechanism further to find the actual targets
of HDACs.