To do that, large compounds libraries are tested on
a biological model showing a specific therapeutic target.
Not exact matches
Darin Kingston of d.light, whose profitable solar - powered LED lanterns simultaneously address poverty, education, air pollution / toxic fumes / health risks, energy savings, carbon footprint, and more Janine Benyus, biomimicry pioneer who finds
models in the natural world for everything from extracting water from fog (as a desert beetle does) to construction materials (spider silk) to designing flood - resistant buildings by studying anthills in India's monsoon climate, and
shows what's possible when you invite the planet to join your design thinking team Dean Cycon, whose coffee company has not only exclusively sold organic fairly traded gourmet coffee and cocoa beans since its founding in 1993, but has funded dozens of village - led community development projects in the lands where he sources his beans John Kremer, whose concept of exponential growth through «
biological marketing,» just as a single kernel of corn grows into a plant bearing thousands of new kernels, could completely change your business strategy Amory Lovins of the Rocky Mountain Institute, who built a near - net - zero - energy luxury home back in 1983, and has developed a scientific, economically viable plan to get the entire economy off oil, coal, and nuclear and onto renewables — while keeping and even improving our high standard of living
So a proper understanding of punc eq and allopatric specation
shows that «gaps» supposedly flow right out of their
biological model of evolution — not merely geology.
These computer simulations of an abstract
model (closely related to the features which characterize self - organizing chemical and
biological systems) clearly
show that the origin of intrinsic capacity for self - definition can be understood in detail, at least in relatively simple cases.
«Tumble - proof cargo transporter in
biological cells: New
model shows how collective transport by synthetic nanomotors along biopolymer filaments can be effectively directed.»
Not only can synthetic molecules mimic the structures of their
biological models, they can also take on their functions and may even successfully compete with them, as an artificial DNA sequence designed by Ludwig - Maximilians - Universitaet (LMU) in Munich chemist Ivan Huc now
shows.
«Folding biomolecule
model shows how form dictates function: New theoretical calculations of the conformation of very large biomolecules helps in understanding interactions with DNA strands as part of
biological functions.»
«Our study
shows how application of interdisciplinary statistical approaches, coupled with informed
models of collective motion can help extract useful
biological information about social interactions in schools of fish.
In fact, they
show that, with sufficient understanding of the eco-evolutionary dynamics and input from mathematical
models, cancers can be steered into a less invasive growth pattern with the application of small
biological force.
«This [concept] has been previously described in other
biological processes, such as circadian rhythmicity, the cell cycle, and even stem cell pluripotency, but is
shown here through a systematic analysis of a data - driven computational
model.»
«Both the neuronal and average human membrane
models — arguably the most compositionally complex plasma membrane lipid
models to date —
showed non-ideal lateral lipid mixing at different length and time scales, demonstrating the inherent complexity of
biological membranes.»
This case study
shows the reliability and efficiency of QMC for characterizing the binding energies for
biological systems, providing a critical input for improved drug
modeling efforts.
The efficient genome editing
shown here demonstrates that these pigs can serve as a powerful tool for dissecting in vivo gene functions and
biological processes in a temporal manner and for streamlining the production of genome - edited pigs for disease
modeling.
Show in the above figure (Figure 2d from the article) is the D'Arrigo et al tree - ring based NH reconstruction (blue) along with the climate
model (NCAR CSM 1.4) simulated NH mean temperatures (red) and the «simulated tree - ring» NH temperature series based on driving the
biological growth
model with the climate
model simulated temperatures (green).
Coupled simulations, using six different
models to determine the ocean
biological response to climate warming between the beginning of the industrial revolution and 2050 (Sarmiento et al., 2004),
showed global increases in primary production of 0.7 to 8.1 %, but with large regional differences, which are described in Chapter 4.
Various
biological modelling studies have indeed
shown remarkable sensitivity to the exact form of the equations used (Wood and Thomas, 1999; Gross et al., 2004; Fussmann and Blasius, 2005).
Two
model homes would
show off systems that handled «
biological nutrients» and «technical nutrients» 40 further homes would showcase integrated potable and grey water community systems, and a biomass gasification facility for homes» heating and cooking.
The conceptual
model showing two potential
biological, indirect pathways from protective parenting to self - reported young adult poor health.
Regression
modeling for the 4 most common disciplinary practices
showed (P <.05) that black race, lack of Aid to Families With Dependent Children receipt, more - educated mothers, and female sex of child were associated with higher use of teaching or verbal assertion; a
biological father in the home was associated with less use of limit setting; and black race and report for child maltreatment were associated with more use of mild spanking.
From early
models, temperament has been thought to have a constitutional basis.1 Recent evidence is
showing that polymorphic variation in dopamine - related genes is associated to individual differences in EC and attentional control.16 However, the relevance of the
biological endowment for EC does not mean that this ability can not be influenced by experience.