Taken together, our results provide for the first time the evidence of
the biological significance of IRF - 9 / STAT2 complex, and furnish an alternative pathway modulating the expression of IFN - stimulated genes, contributing to the diversity of IFN signaling to mediate their multiple biological properties in normal and tumor cells.
This focus on rigor and on
the biological significance of the study sets MCP apart and above other proteomic journals.
To determine
the biological significance of the ant strength α, we performed the compression test on three different ants with an average weight of 1.1 ± 0.15 mg.
The team's findings (to be published this autumn in Animal Behaviour) also bring new evidence to bear on ancient sexual conundrums such as
the biological significance of masturbation.
Previous research has shown that HIV - 1 integrates more frequently into human genes that are transcribed into RNA (the first step in gene expression), but
the biological significance of this targeting has been unclear.
Endothelial cells can produce substantial amounts of ammonia, but
the biological significance of this gas in these cells is not known.
Although researchers do not yet know
the biological significance of these discoveries, they say that fully cataloguing the genome may help them understand how genetic variations affect the risk of contracting diseases such as cancer as well as how humans grow from a single - celled embryo into an adult.
Such recommendations misrepresent the true function and
biological significance of the behaviors, and the critical extent to which dangerous practices can be modified, and they dismiss the valid reasons why people engage in the behavior in the first place.
Right before the First World War, another Harvard chemist, Lawrence Henderson, reworked large parts of Cooke's argument (without crediting him for it) in a more secular form, in another book with an illustrative title, The Fitness of the Environment: An Inquiry Into
the Biological Significance of the Properties of Matter.
In both cases psychicalistic ideas were useful in arriving at some empirical facts, for example, about the composite nature of «loudness» as a variable of sense experience (Hartshorne 1934, pp. 61 - 72), or
the biological significance of «highly developed» bird song, or of contrast and uncertainty in the sequence of songs or phrases (Hartshorne 1973, pp. 106 - 112, 117f, 119 - 136, 151 - 188).
Not exact matches
What is the ultimate
significance of the nuclear or
biological family, the family
of origin?
If genetic inheritance and social inheritance combine to predispose us to behavior with moral
significance, then we can hypothesize that some level
of biological and environmental determinism has an effect on everyone's life.
And it denies that sex has any real moral or social
significance, downgrading it by default to a mere recreational form
of biological activity.
«Anthropological reflection, in fact, leads to the recognition that, by virtue
of the substantial unity
of body and spirit, the human genome not only has a
biological significance, but also possesses anthropological dignity, which has its basis in the spiritual soul that pervades it and gives it life.»
It is not sufficient because any purely
biological descriptionrequires some interpretation
of its anthropological and moral
significance before it can function as a guide to action.»
The term is typically reserved for those purposes which are
of biological significance, but are not otherwise established as essential nutrients.
Although the effects
of maternal food supplements on mean birthweight are relatively small, because
of their influence across the population distribution they have great
biological significance.
As a result, until the last two decades
of the 20th century, few scientists spent time studying a topic thought to have little, if any,
biological significance.
She received the chemistry Nobel Prize in 1964 for the structure
of B - 12 «and other molecules
of biological significance.»
The
significance of the new model, according to Grange, is that «it enables us to now have a
biological understanding
of the patterns, the co-expression profiles, seen in the Allen Gene Expression Atlas
of the Mouse Brain.»
The study from the University
of Waterloo is published in the Journal
of Biological Chemistry today and is featured as the «Paper
of the Week» for its
significance.
Moreover, quite apart from their
biological significance, the new findings are
of considerable physical and mathematical interest, Huber adds: The underlying phenomenology
of our model differs fundamentally from that conventionally used in modelling the behavior
of powered or active particle systems.
The report, released today by the Natural Resources Defense Council (NRDC) and the International Union for Conservation
of Nature, maps out 13 areas that are
of particular ecological and
biological significance or are especially vulnerable to human intrusion.
«Our study has great
biological and medical
significance, particularly in light
of the huge disease burden
of malaria,» said senior author Manoj Duraisingh, John LaPorte Given Professor
of Immunology and Infectious Diseases.
An improved understanding
of the
biological background
of musical aptitude can contribute new insights into, for instance, genes that affect normal brain functions, the interactions between genes and the environment and the
significance of music as a form
of therapy.
Not only does MCP require proteomics data to be
of good quality and to be held to a high standard
of rigor, but MCP also requires authors to demonstrate clearly the
biological or biochemical
significance of their data.
In the case
of sequence data, metadata can encompass what organism or cell was sequenced, where it came from, what it was doing, quality metrics, and a spectrum
of other characteristics that add value to the sequence data by providing context for it and enabling greater
biological understanding
of the
significance of the sequence.
All night - time
biological processes were found with high
significance of FDR p - value < 0.05.
All
biological processes that were analyzed from total and unique genes were found with high
significance of FDR p - value < 0.05, except
of «connective tissue development» cluster within the
biological process cartilage and bone biogenesis, with FDR p - value
of 0.068.
These mouse models are useful tools to improve our understanding
of the
biological significance and functional relevance
of these polymorphisms in human disease, particularly when validated with controlled exposures and environmental challenges.
Some reasons for this relatively low yield include unappreciated phenotypic heterogeneity; locus heterogeneity; somatic and germline mosaicism; variants
of uncertain functional
significance; technically inaccessible areas
of the genome; incorrect mode
of inheritance investigated; and inadequate communication between clinicians and basic scientists with knowledge
of particular genes, proteins, or
biological systems.
The limited infectivity
of persisting non-cultivable B. burgdorferi has no
biological significance for the natural enzootic cycle
of B. burgdorferi, but it remains to be determined if they have
significance in the post-treatment host.
Because
of dynamic movement and nonsimilar workout habits, large SDs and lack
of significance from control preclude statistical and
biological significance.
One such complex
of considerable
biological and industrial
significance is the
Her Body Art is imbued with political
significance, undermining the traditional erotic representations
of women by male artists, and often exposes the inner
biological systems
of females as a metaphor for hidden social issues.
The parallel between Moore's artistic «invasion»
of the city and the mussels»
biological invasion
of the Great Lakes has both international
significance and local relevance.
However, some small differences were observed, though these fell within the normal variation range
of the considered parameter and thus had no
biological or toxicological
significance.
Awareness
of the direct impacts
of carbon dioxide on the oceans has been slow to build in part because research on the flood
of this and other greenhouse gases focused for so long on the climatological
significance, not the direct chemical and
biological effects.
In speaking
of future partnerships, Mr. Sullivan stated that the groups are collaborating with Scenic Hudson on its Saving the Land That Matters Most initiative to protect 65,000 threatened acres throughout the Hudson Valley that have been deemed by the state to have the highest scenic and / or
biological significance.
But Adelie Penguins winter on ice floes north
of the Antarctic Circle during the winter, and Ainely agrees warming winter trends on land have no
biological significance for Adelies.
Federally recognized as «lands
of national
significance,» the Hudson Highlands have been described as one
of the world's great «
biological melting pots» because
of the astonishing diversity
of wildlife they support.
Such issues are
of particular
significance for studies
of climate impacts, which may, for example, represent linkages between physical and social science, as well as feedbacks among physical, chemical and
biological systems.
The Ramsar Convention is directly linked to the Convention on
Biological Diversity and Ramsar wetlands are recognised as a matter
of national environmental
significance under the Environment Protection and Biodiversity Conservation Act 1999.