I, along with many
biology of aging experts, believe strongly that glucose is a major cause of molecular damage in all life and that it contributes to aging.
As one of the three initial cores established when the Buck Institute was founded, the Genomics Core has played a vital role in helping shape investigations in the basic
molecular biology of aging, from assisting in the investigation of how specific drugs can extend lifespan in simple model organisms such as the nematode C. elegans, to facilitating studies in various animal models of age - related disease.
«There's dogma in the literature — which is more oriented toward the
cell biology of aging — that wild animals don't actually senesce,» says Daniel Nussey, an evolutionary ecologist at the University of Edinburgh who studies aging in Soay sheep on a remote Scottish island.
Rather than despairing that combinatorial interactions of diets, nuclear genes, and mitochondrial genes make the
underlying biology of aging intractably complex, Rand and lead author Chen - Tseh Zhu said studies that explicitly embrace such multifactorial interactions can lead researchers to understand the inherent biological complexity of the aging process: Many genes, many cells, and many environments all contribute to the aging process.
Meanwhile, tuning in to other research themes, Finch has delved into the
comparative biology of aging, a topic he surveyed in detail in his 1990 book, Longevity, Senescence, and the Genome, a 922 - page tome.
By understanding the
underlying biology of aging, she notes, it may be possible to develop drugs in the future that will promote healthy aging and delay age - related diseases such as some cancers, arthritis, diabetes, high blood pressure and heart disease.
Tom Kirkwood of Newcastle University, UK, disagrees with the idea of a limit to human lifespan: «The idea does not really fit what we already know about
the biology of the ageing process.
Muller, a native of Munich who grew up in Germany and France, had his curiosity captured by
the biology of aging when he was 12.
The local library had an Internet connection, and he started surfing the Web to learn more about
the biology of aging.
She runs the NIA training grant program in
the biology of aging at the Sam and Ann Barshop Center for Longevity and Aging Studies at UTHSCSA, and last year she organized a gerontology course for grad students and postdocs.
As assistant director of the Institute of Healthy Aging at University College London, Gems regularly runs experiments on Caenorhabditis elegans, a roundworm that is often used to study
the biology of aging.
It is with insulin and IGF that the genetics and
biology of aging are finally coming together.
«What I tell people,» says Steven Austad, an expert on
the biology of aging at the University of Texas Health Science Center, «is that if you want to live to be a healthy 80 - year - old, you have to eat right and exercise, et cetera.
While many scientists in
the biology of aging field may now find it helpful to reconcile disparate results of the past, Hart said, the new findings should also give them pause about continuing to use FUdR in the future.
When researchers have looked at single or even pairs of factors in a wide variety of organisms, they've made many valuable findings about
the biology of aging, Rand said.
Recent advances in the molecular
biology of aging have yielded a host of candidates.
In 2015, ISRIB was licensed to the secretive Google spinout company Calico, which studies
the biology of aging and life span.
Clark and other leaders in the field have for years informally lobbied E.C. bureaucrats to bolster financial support of research on
the biology of aging.
«I thought that with the development of molecular biological techniques, we could ask and answer important questions in
the biology of aging, which researchers couldn't [answer] up to that time.»
Drawing upon his old connections at Cambridge and beyond, Clark is one of a cadre of European scientists who've been fostering international research collaborations on
the biology of aging.
But the current Framework agenda, FP6, has proved a big disappointment, providing «shockingly low» support for
the biology of aging, Clark says.
The joint venture, which is supported by the AARP Andrus Foundation, is intended to profile the careers of individuals working to further our understanding of
the biology of aging.
Wake - Up Call A software engineer is the last person you'd expect to see dissecting
the biology of aging.
Tying It Together Rudi Westendorp is one of those rare individuals whose work unites geriatrics, clinical epidemiology, and
the biology of aging.
Rudi Westendorp is one of those rare individuals whose work unites geriatrics, clinical epidemiology, and
the biology of aging.
Today, Aarhus University is one of the few places in Europe that offers a full - semester course on
the biology of aging, which Rattan teaches.
The initiative promoted networking and brainstorming among scientists who were investigating the diseases and
biology of aging.
The journal received a Silver award for the cover design of its 4 December 2015 special section on
the biology of aging.
«Given the Buck's exclusive focus on aging, we believe that there's great potential to increase our understanding of
the biology of aging and to accelerate the translation of emerging insights into therapies to help patients with age - related diseases.»
The Buck Institute and the GFMR have partnered to co-fund 10 postdoctoral fellowships with the objectives of (1) training and preparing future leading researchers in the mechanisms of biological aging and its relationship to the chronic conditions of aging; and (2) promoting leading research into
the biology of aging.
Researchers and scientists are now discovering ways to eliminate malaria, increase healthy behavior, reduce the toll of chronic disease, improve the health of mothers and infants, and change
the biology of aging.
And while known lifestyle adjustments already promote wellness and skirt many diseases, this demographic fact makes it imperative that research on
the biology of aging be expanded along the course set by the Minnesota team.
Barzilai, who is the trial's lead investigator, says instead, «I think of
the biology of aging as the risk factor for all of those diseases, and that's what we want to target.»
Long an advocate of progressive ideas and causes, he has focused on providing legal services to business that focus on
the biology of aging and regenerative medicine.
«What we want is to live longer, healthily,» Steven Austad, Ph.D., said, speaking at a recent course on
the biology of aging at the MDI Biological Laboratory on Mount Desert Island.
Repair;
The biology of aging convincingly shows nutrient sensors including insulin for glucose and mTOR for protein, control a genetic pathway that is almost universally conserved among all animal life from single celled yeast onward to humans.
There are many «studies» on many animals based on the science of
the biology of aging that have been published.
I believe that Jaminet's diet can improve one's health, but if you want to go to the next frontier, to that frontier where it is possible to slow down the effects of aging and reverse to a great extent many of the chronic diseases of aging, as revealed by calorie restriction and other elegant studies being done by scientists around the world studying
the biology of aging, such as Cynthia Kenyon, you will have to take the next step that my diet will take you to.
Because when it comes to
the biology of aging, the state is virtually a blank slate.