The potential for this to be useful was obvious — both in understanding the molecular and
cellular biology of the disease, but also for drug discovery and screening.
Current therapies are focused principally on symptomatic relief, due in part to a lack of understanding of the
basic biology of the disease.
Any insight into the fundamental genetics and
overall biology of the disease is valuable to improve future interventions and reduce rates of infection and mortality.»
The St. Laurent Institute, a non-profit medical research institute focused on the
systems biology of disease, today announced in a study published in the July edition of Genome Biology, that genetic matter, previously ignored by the scientific community, may play an important role in cancer.
Bethesda, MD About Blog The official journal of the American Society for Investigative Pathology, examining the cellular and
molecular biology of disease.
Research yields promising drug targets impacting
underlying biology of the disease; Findings form the basis of deCODE's most advanced drug discovery program Reykjavik, ICELAND, July 24, 2002 — deCODE genetics (Nasdaq / Nasdaq Europe: DCGN) today announced the publication...
The finding that fibrolamellar can spread to the brain doesn't immediately add to scientists» understanding of
the biology of the disease, Simon says, but is nevertheless significant as it may offer immediate ways to improve treatment.
But now, building on a deep understanding of
the biology of the disease, biologists have produced a breakthrough drug that is on the brink of regulatory approval.
The work, which was propelled by technologies that enable the detailed analysis of even a handful of cells, opens a critical window on
the biology of the disease and suggests a strategy for the development of more precise, powerful treatments.
At a recent meeting, they clarified
the biology of this disease, which has stricken trees in the Western United States while raising mysteries about its origin.
Neither of the breathing retraining interventions (exercises) improved lung function or airway inflammation, suggesting they were not affecting the underlying
biology of the disease.
«Our results reflect the importance of lifelong follow - up for individuals diagnosed as having MGUS, independent of risk score, and highlight the need for better risk models based on
the biology of the disease.
«Better understanding
the biology of diseases can eventually lead to better treatments for some of the most complex and challenging diseases, like cancer.»
«We also hope to understand
the biology of the disease better by determining why these proteins are higher in women with pre-eclampsia and whether they have a role in the development of the placenta.»
When developing a new drug, researchers identify drug targets based on what they know about
the biology of the disease, and then create compounds that affect those targets.
Bladder cancer is the fifth most common cancer in the United States, yet it is one of the least understood because few animal models reflect
the biology of the disease.
In addition to allowing examination of
the biology of these diseases, the FACC - 29 will help researchers test new targeted cancer treatments and other therapeutics against authenticated cell lines, predicting which cancers will and will not respond.
Scientists have made some progress in the last decade to understand
the biology of the disease at the cellular level, but advances in clinical outcomes have not kept pace.
These two groups of long - term and short - term survivors hint at differences in
the biology of the disease, Spellman says.
We have to be in a position to compare genomes and clinical data if we want to learn and if we want to help people, like give them accurate predictions or learn
the biology of a disease.
However, understanding the genetic variants underlying susceptibility to testicular cancer also helps us understand
the biology of the disease, which may in due course inform development of new targeted therapies that could be effective in patients resistant to platinum chemotherapy.
By pairing engineered cell lines containing disease - specific mutations with high throughput screening, we can investigate the role of given mutations in
the biology of disease as well as identify potential druggable targets.
«We believe that these findings will lead to a better understanding of
the biology of this disease.
The feasibility of applying such a model was considered with
the biology of the disease, regulatory concerns, and pharmaceutical needs in mind.
The findings could help improve the assessment of individuals» risk and point researchers to clues about the underlying
biology of this disease, which is the second leading cancer killer in the U.S.
«This research opens the door for new studies to look in depth at
the biology of the disease and how this alteration in particular may exert its effect.»
The American Journal of Pathology seeks to publish high - quality, original papers on the cellular and molecular
biology of disease.
Bethesda, MD About Blog The official journal of the American Society for Investigative Pathology, examining the cellular and molecular
biology of disease.
The American Journal of Pathology seeks to publish high - quality, original papers on the cellular and molecular
biology of disease.
Bethesda, MD About Blog The official journal of the American Society for Investigative Pathology, examining the cellular and molecular
biology of disease.
The American Journal of Pathology seeks to publish high - quality, original papers on the cellular and molecular
biology of disease.
Bethesda, MD About Blog The official journal of the American Society for Investigative Pathology, examining the cellular and molecular
biology of disease.
Bethesda, MD About Blog The official journal of the American Society for Investigative Pathology, examining the cellular and molecular
biology of disease.
The American Journal of Pathology seeks to publish high - quality, original papers on the cellular and molecular
biology of disease.