«The goal is to find specific
biomarkers of aggressive cancers,» said Charles Brendler, MD, Co-Director of the John and Carol Walter Center for Urological Health & Program for Personalized Cancer Care at NorthShore and author of the study.
Not exact matches
Two Northwestern University scientists have identified a
biomarker strongly associated with basal - like breast
cancer, a highly
aggressive carcinoma that is resistant to many types
of chemotherapy.
'' (In the context
of prostate
cancer) there's a big interest in trying to find
biomarkers to discriminate between
aggressive and nonaggressive disease,» said Renny Franceschi, U-M professor
of dentistry, biological chemistry and biomedical engineering.
The research ideas you develop at the workshop should: • Lead to the significant advancement
of our understanding
of sensor technologies suitable for liquid biopsy • Consider the practical challenges
of low volume liquid usually taken for analysis and the inconsistency
of sample preparation across point
of care sites • Prioritise
biomarkers with high specificity for
cancer or even for multiple
cancer types, including markers specific to
cancers that will become
aggressive as opposed to non-lethal disease
In a collaborative effort with UCLA Medical Centre, the goal
of this project is to investigate cell nanomechanics, namely cell stiffness or elasticity, and related changes
of the actin cytoskeleton as a potential
biomarker for
aggressive cancers.