The U.S.
biomedical research system, including labs such as this one at the National Institutes of Health, is in need of reform, according to four prominent researchers.
scientific leadership to be bold in ensuring the future of our nation's remarkably successful
biomedical research system.
Not exact matches
Brendan Frey, CEO of Deep Genomics and a
biomedical engineering professor at the University of Toronto, says his
research team trained its
system to analyze individual cells to draw conclusions about the entire cellular
system and, ultimately, make a diagnosis.
Isaac has more than a decade of
research experience in
biomedical science and life cycle assessment of energy and agricultural
systems.
This
research investigates their strategic articulation of the discrepant knowledge
systems with which they are confronted: their traditional
system, the
biomedical system, and the new professional midwifery
system.
Another call to reform
biomedical research and training Beryl Benderly, Jim Austin, 14 April Four prominent scientist - administrators call on policymakers to reform a
system that discourages «even the most outstanding prospective students from entering our profession.»
Then, this past April, she teamed up with three other scientific superstars — Bruce Alberts, former president of the National Academy of Sciences and former editor - in - chief of Science; Marc W. Kirschner, founding chair of the Department of
Systems Biology at Harvard Medical School; and Harold Varmus, Nobel laureate, former director of NIH, and current director of the National Cancer Institute — to publish «Rescuing US
biomedical research from its systemic flaws,» a critique and call for reform that seems already to have altered the course of the workforce debate, in the Proceedings of the National Academy of Sciences (PNAS).
The Department of
Systems Biology at Harvard Medical School in Boston has 20 faculty members (including departmental faculty, affiliated faculty, visiting faculty, instructors, and lecturers) working on
biomedical research projects.
«The misalignment of resources in
biomedical research could be likened to poor budgeting of household finances,» said senior study author Andrey Rzhetsky, PhD, professor of genetic medicine and senior fellow at the Institute for Genomics and
Systems Biology at the University of Chicago.
The MDC researchers are fascinated by the new opportunities the CRISPR - Cas9
system offers for
biomedical research, but strictly reject genetic modification of the human germline.
One factor is that the goals of obtaining a grant and making a breakthrough discovery are increasingly at odds, warn Bruce Alberts, former president of the National Academy of Sciences and former editor - in - chief of Science; Marc W. Kirschner, founding chair of the Department of
Systems Biology at Harvard Medical School; Shirley Tilghman, former president of Princeton University; and Harold Varmus, Nobel laureate and former director of the National Cancer Institute, in a highly publicized critique of U.S.
biomedical research that was published in April 2014.
«I have already ensured that the issues surrounding CIHR and its reforms will be considered by the panel, and I look forward to their advice,» wrote Philpott, who also noted that «I expect CIHR to ensure that the very best health
research across all pillars [
biomedical; clinical; health
systems and services; and social cultural, environmental factors that affect the health of populations] is funded according to the highest international standards of
research excellence.»
Yet even as teams developed the CRISPR / Cas9 gene - editing
system for
biomedical and basic
research purposes, multiple groups have been on the lookout for better versions of the molecular scalpel.
«With Teresa Woodruff's
research using Draper's human organ
system platform, we have a compelling demonstration of the importance of a microenvironment that permits cells to function in vitro as they would in vivo, and the power of being able to interconnect organ models on a platform and operate them in a stable and precise manner for weeks to months,» said Jeffrey T. Borenstein, a
biomedical engineer at Draper.
«In the United States, since World War II when this basic
system was created,
research has been a kind of Ponzi scheme in the sense that when the government provides grants, the institution leverages the indirect costs to expand
research... and no institution has the resources to support the size of the faculty they have, especially in the
biomedical sciences.»
The discussion that follows uses the National Institutes of Health (NIH)
system as example, as this is the largest source of
biomedical research funding.
Five researchers who study a cellular
system for fixing misfolded proteins, deep brain stimulation for Parkinson's disease, and breast cancer genetics have won this year's prestigious Lasker Awards for
biomedical research.
The
research has important implications for the fundamental understanding of translation in living
systems, as well as intriguing potential in the
biomedical arena.
The invention, called a «nonlinear mirror» by the researchers, could help advance nonlinear laser
systems that are used for chemical sensing, explosives detection,
biomedical research and potentially many other applications.
By using the R21 activity code, the NIH seeks to foster the introduction of novel scientific ideas, model
systems, tools, agents, targets, and technologies that have the potential to substantially advance
biomedical research.
The Institute for
Systems Biology is a nonprofit
biomedical research organization based in Seattle.
«We have a
system that has worked well in the past, that has made the U.S. the leader in
biomedical research worldwide,» he says, «and while I don't think we've lost that [edge] yet, we do see a rising tide in lots of places.»
Very fortunately, a new
biomedical funding
system called AMED (Japan Medical
Research and Development Agency) is coming in the next fiscal year, 2015.
Theranostics publishes innovative
research articles reflecting the fields of in vitro diagnostics and prognostics, in vivo molecular imaging, molecular therapeutics, image - guided therapy, biosensors,
system biology and translational medicine, personalized medicine and a broad spectrum of
biomedical research that can be applied to future theranostic applications.
With her recent groundbreaking findings in the field of RNA - mediated regulation based on the CRISPR - Cas9
system, E. Charpentier has laid the foundation for the development of a novel, highly versatile and specific genome editing technology that is revolutionizing life sciences
research and could open up whole new opportunities in
biomedical gene therapies.
ABOUT LA JOLLA INSTITUTE Founded in 1988, the La Jolla Institute for Allergy and Immunology is a
biomedical research nonprofit focused on improving human health through increased understanding of the immune
system.
Systems biology is an approach to biomedical research in which scientists combine complex «omics» datasets to develop a more complete understanding of complex biological systems, such as the regulation of whole genome - level transcription, regulation of the 3D genome, the role of signaling and metabolic pathways in disease, an
Systems biology is an approach to
biomedical research in which scientists combine complex «omics» datasets to develop a more complete understanding of complex biological
systems, such as the regulation of whole genome - level transcription, regulation of the 3D genome, the role of signaling and metabolic pathways in disease, an
systems, such as the regulation of whole genome - level transcription, regulation of the 3D genome, the role of signaling and metabolic pathways in disease, and more.
My work spans
research in photonic devices, optical
systems engineering, optimization, computer vision, and
biomedical applications.
The origin of the mouse as the principal model
system for
biomedical research dates back to the start of human civilization.
The Institute for
Systems Biology is a nonprofit
biomedical research organization based in Seattle, Washington.
The ASHG Advocacy Award, new in 2015, honors individuals or groups who have exhibited excellence and achievement in applications of human genetics for the common good, in areas such as facilitating public awareness of genetics issues, promoting funding for
biomedical research, and integrating genetics into health
systems.
Dr. Hyder has studied
biomedical ethics, conducted surveys on
research ethics, participated in the training of African and Asian health professionals in ethics, and explored health
systems ethics including specific issues such as standard of treatment and ancillary care.
«The Gene Editing Institute exists within a community hospital
system where we are committed to a patient - first approach to
biomedical research.
In most situations, an ABS - equipped car will come to a stop in a shorter distance than a car without the
system, said Dave Viano, head of GM's
biomedical research department.
The college has expertise in public health,
biomedical and comparative medical
research, ecosystem and environmental management, and the multiple facets that compose our complex global food
system.
In addition to caring for the health needs of all animals they provide expertise to our global food
system, conduct
biomedical and agricultural
research, offer ecosystem management, and serve as public health officers.
PBS Kansas is dedicated to promoting
research - based strategies that combine applied behavior analysis and
biomedical science with person - centered values and
systems change to increase quality of life and decrease problem behaviors.