Sentences with phrase «biopsied tumor samples»

«We used biopsied tumor samples from DIPG patients to create models in the lab, which we studied and then used to test a novel, targeted approach to treating the tumor.

Not exact matches

Interest in liquid biopsy has escalated in recent years due to the minimally invasive sampling method, potential to overcome the challenges of tumor heterogeneity, and the potential for longitudinal monitoring of tumor burden through serial sampling.

The focus of those hopes is the liquid biopsy: a test that could detect and analyze a solid tumor from biomarkers in the bloodstream or other easily sampled body fluids, such as saliva.

«The minimum sample volume required is only 1 µL for analysis of 92 proteins, which has been proven to be a great advantage for applications with limited sample volumes, such as pediatric applications, fine - needle biopsies, and tumor microbiopsies,» he says.

Even after initial purification of the sample, liquid biopsies typically contain much more nucleic acid from healthy cells than from tumors.

While more sensitive assays have enabled doctors to take smaller samples of some types of solid tumors, oncologists have long dreamed of avoiding traditional biopsies altogether.

Biopsied samples of glioblastoma tumors contain high level of STK17A.

In addition, it was difficult to study these tumors because they were rarely biopsied and tissue samples were rare.

A tissue slice, a tumor biopsy, or a sample of a bacterial culture yields a sequence representing the average of all of the cells within it, even though researchers know there can be tremendous variation between those cells.

The research team analyzed BRAF inhibitor resistance in melanoma cell lines, mice bearing human melanoma tumors, and in human tumor biopsy samples.

«With liquid biopsies, we don't have to wait for tumor growth to get a DNA sample,» says Dr. Vasmatzis.

Investigators compared DNA from the liquid blood biopsies to DNA tissue samples from the tumor, using mate - pair sequencing — an inexpensive whole exome sequencing that can reveal genetic changes that contribute to tumor growth.

Cells were extracted from the biopsy of her tumor sample for use in research without her knowledge or consent.

Rather than wait for tumor biopsy samples to become available, scientists captured «cell - free» DNA shed into the bloodstream by the tumor cells.

Guided by a camera and the ultrasound probe, Waxman carefully positioned the endoscope over the tumor and passed a fine needle into the pancreatic lesion to sample tissue cells for biopsy.

3/24/2008 Non-Invasive Imaging Provides Window Into Genetic Properties of Brain Tumors Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or suTumors Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or sutumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery.

Biopsy, samples removed from the tumor and examined to confirm diagnosis of a specific type of tumor

The team will capture the tumor samples» genomic and transcriptomic data as well as the clinical outcomes and drug responses of each patient, starting with 842 participants and the already - collected tumor biopsies from 3,000 tumor regions among them.

In many cases cancers can be diagnosed by withdrawing a sample of tumor cells with a small needle, while in other cases a surgical biopsy may be performed.

If your dog is female, your vet can use a cytoscope — a tiny camera threaded into the bladder — to view the tumor or collect a sample for biopsy.

Diagnosis of oral SCC requires a biopsy of the tumor with the cat under general anesthesia so that a good sample of the tumor can be collected.

A biopsy is very different from a needle sample of a tumor (fine - needle aspirate), where cells are drawn out with a needle and placed on a slide to be examined under a microscope.

To diagnose, your a veterinarian either removes the tumor or takes a sample, sending the biopsy to a lab for analysis.

Since the biopsy procedure only samples the mucosa it is possible to miss detecting a tumor that involves only the deeper layers of the intestinal tract.

If the tumor is behind the eye, there is a special tool (fine - needle aspirate) that will allow your veterinarian to take a sample (biopsy).

Tumor samples may ultimately be collected from cats undergoing surgical biopsies and formalin fixed.

Next, a biopsy or tissue sample of the tumors, or any excessive fluids that have collected in body cavities, may be taken and analyzed.

Histopathology is the microscopic examination of specially prepared and stained tissue sections from the tumor biopsy sample.

The diagnosis is made based on history, x-rays of the bone and ultimately a biopsy, or removal of a tissue sample from the tumor.

Various sampling procedures may be needed such as needle aspiration, punch biopsy, full excision biopsy or exploratory surgery (for tumors in the abdomen).

Various sampling procedures may be needed, and may include needle aspiration, punch biopsy, full excision biopsy or exploratory surgery (for internal tumors).

Ultrasound can help our doctors assess cardiac function, manage heart disease, obtain non-surgical biopsy samples, locate abdominal tumors, metastasis, and much more.

Your veterinarian will submit the tissue samples, either a biopsy or small part of the tumor or the entire mass, to a specialized laboratory.

The histopathology report will include information on the type and grade of tumor (the type of cells and their degree of resemblance to normal cells), how it is likely to behave (the prognosis) and whether, if the sample represented an excision biopsy, the cancer has been fully removed.

A cystoscope is a long, thin, tube - shaped instrument with a camera on the end of it, which is used to nonsurgically obtain biopsy samples from tumors inside the bladder and urethra.

A specific tumor type can be suspected from its appearance on a CT or MRI, but can only be definitively identified by taking a sample of the tumor, either at surgery or by biopsy.

Additionally, veterinarians usually want to take a fluid sample from the lymph nodes to look for cancerous cells and will perform a biopsy of any oral mass to determine exactly what kind of tumor is present.

Due to advances in veterinary medicine, tests can be applied to mast cell tumor biopsy samples to determine if certain chemotherapeutic agents should be used for treatment.

Three pathologists examine the punch biopsies, along with the complete tumor samples, to determine the grade of mast cell tumor.

The goal of this study is to compare the histopathological grade of samples obtained from a punch biopsy to samples obtained from a whole tumor specimen.