Sentences with phrase «bitter saccharin»

Not exact matches

So it's probably the actions of cyclamate at saccharin's bitter receptors that help block the bitterness, Behrens and his colleagues report September 14 in Cell Chemical Biology.

In this case, though, the amount of saccharin required to block the receptors that cyclamate activates would have bitter effects on its own.

So with cyclamate around, saccharin can't get at the bitter taste subtypes, Behrens explains.

It turns out that saccharin doesn't just activate sweet taste receptors, it also blocks bitter ones — the same bitter taste receptors that cyclamate activates.

The reverse was true, too: Saccharin blocked TAS2R1 — one of the bitter receptors that cyclamate activates.

Behrens and his colleagues Kristina Blank and Wolfgang Meyerhof developed a way to screen which of the bitter taste receptors that saccharin and cyclamate were hitting, to figure out why the combination is more palatable than either one alone.

Compounds like saccharin are potent sweeteners, but new research suggests they could be a bitter pill for some gut microbes.

Saccharin and cyclamate both have bitter ends.

So with cyclamate around, saccharin can't get at the bitter - taste receptors it normally triggers, Behrens explains.

Blends of non-caloric sweeteners saccharin and cyclamate show reduced off - taste due to TAS2R bitter receptor inhibition.

It also blocks the bitter receptors that saccharin stimulates.

Previous studies of the two sweeteners had shown that saccharin activates the bitter receptor subtypes 31 and 43.